{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T22:04:23Z","timestamp":1770761063311,"version":"3.50.0"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T00:00:00Z","timestamp":1354752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">ADEM<\/jats:styled-content> is a rare inflammatory demyelinating disease of the <jats:styled-content style=\"fixed-case\">CNS<\/jats:styled-content>, which usually presents after a viral infection or a vaccination. We report a 15\u2010yr\u2010old boy who was diagnosed with <jats:styled-content style=\"fixed-case\">ADEM<\/jats:styled-content> after an <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010identical sibling allogeneic <jats:styled-content style=\"fixed-case\">BMT<\/jats:styled-content> for transfusion\u2010dependent <jats:styled-content style=\"fixed-case\">PRCA<\/jats:styled-content>. His course was complicated with <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> affecting the skin and lungs. Five months post\u2010<jats:styled-content style=\"fixed-case\">BMT<\/jats:styled-content>, he developed neurological symptoms including sudden mental status alteration, dysarthria, facial nerve palsy, and acute paraplegia. The <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> revealed multifocal hyperintense lesions mainly in the subcortical white matter of the cerebrum, the brainstem, the basal ganglia, and the thalami. <jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content> examination was normal. There was no laboratory evidence of infection. The typical <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> findings and an acute monophasic clinical course were consistent with the diagnosis of <jats:styled-content style=\"fixed-case\">ADEM<\/jats:styled-content>. Clinical and radiological improvement was observed after treatment with high\u2010dose steroids and <jats:styled-content style=\"fixed-case\">IVIG<\/jats:styled-content>. Complete neurologic recovery was achieved six\u00a0months after the onset of symptoms. We present a rare case of <jats:styled-content style=\"fixed-case\">ADEM<\/jats:styled-content> post\u2010<jats:styled-content style=\"fixed-case\">BMT<\/jats:styled-content> and review of the literature.<\/jats:p>","DOI":"10.1111\/petr.12018","type":"journal-article","created":{"date-parts":[[2012,12,7]],"date-time":"2012-12-07T05:08:34Z","timestamp":1354856914000},"source":"Crossref","is-referenced-by-count":6,"title":["Acute disseminated encephalomyelitis after allogeneic bone marrow transplantation for pure red cell aplasia \u2013 A case report and review of the literature"],"prefix":"10.1111","volume":"17","author":[{"given":"Anna","family":"Paisiou","sequence":"first","affiliation":[{"name":"Stem Cell Transplant Unit \u201cAghia Sophia\u201d Children's Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evgenios","family":"Goussetis","sequence":"additional","affiliation":[{"name":"Stem Cell Transplant Unit \u201cAghia Sophia\u201d Children's Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Dimopoulou","sequence":"additional","affiliation":[{"name":"Stem Cell Transplant Unit \u201cAghia Sophia\u201d Children's Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vassiliki","family":"Kitra","sequence":"additional","affiliation":[{"name":"Stem Cell Transplant Unit \u201cAghia Sophia\u201d Children's Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioulia","family":"Peristeri","sequence":"additional","affiliation":[{"name":"Stem Cell Transplant Unit \u201cAghia Sophia\u201d Children's Hospital Athens Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgos","family":"Vessalas","sequence":"additional","affiliation":[{"name":"Stem Cell Transplant Unit \u201cAghia Sophia\u201d Children's Hospital Athens 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