{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:45:13Z","timestamp":1761101113369},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,31]],"date-time":"2013-03-31T00:00:00Z","timestamp":1364688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> is the only proven treatment option for CML, a rare disease in children. Recently, there are promising reports on the advantageous effect of imatinib mesylate for pediatric patients with <jats:styled-content style=\"fixed-case\">CML<\/jats:styled-content>. We conducted a retrospective study on 33 pediatric patients suffering from <jats:styled-content style=\"fixed-case\">CML<\/jats:styled-content>. Fourteen underwent <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> and the rest were treated with imatinib. With a median follow\u2010up of 24\u00a0months, the two\u2010yr <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> group and the imatinib group was 84% and 87%, respectively (p\u00a0=\u00a00.714). The probabilities of two\u2010yr <jats:styled-content style=\"fixed-case\">DFS<\/jats:styled-content> were 59% in the <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> group and 82% in the imatinib group, either (p\u00a0=\u00a00.880). Relapse occurred in 5 (35.7%) patients of the <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> group, and 8 (42.1%) patients showed relapse in the imatinib group. Among nine patients who died, five were in the <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> group and the rest were in the imatinib group. The probability of relapse in the patients of the imatinib group followed up for several consecutive years may be higher than observed in the <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> group, so we cannot easily conclude which way is more reliable.<\/jats:p>","DOI":"10.1111\/petr.12074","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T03:12:43Z","timestamp":1364785963000},"page":"380-386","source":"Crossref","is-referenced-by-count":9,"title":["The treatment of children suffering from chronic myelogenous leukemia: A comparison of the result of treatment with imatinib mesylate and allogeneic hematopoietic stem cell transplantation"],"prefix":"10.1111","volume":"17","author":[{"given":"Amir Ali","family":"Hamidieh","sequence":"first","affiliation":[{"name":"Hematology\u2010Oncology and Stem Cell Transplantation Research Center Tehran University of Medical Sciences Tehran 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