{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T18:39:40Z","timestamp":1778265580583,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T00:00:00Z","timestamp":1372809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">NODAT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content> are well\u2010known complications of immunosuppressive therapy after transplantation being a risk factor for cardiovascular disease affecting patient and graft survival. Therefore, early identification and treatment are of high importance. In this study, we examined the glycemic homeostasis of 20 renal\u2010transplanted children using routine laboratory tests and the continuous glucose monitoring system (<jats:styled-content style=\"fixed-case\">CGMS<\/jats:styled-content>). Six patients (30%) had <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content>, and one patient had <jats:styled-content style=\"fixed-case\">NODAT<\/jats:styled-content> (5%). The <jats:styled-content style=\"fixed-case\">HOMA<\/jats:styled-content> index was in an abnormal range in 35% of all patients and was abnormal in 67% of the <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content> patients. <jats:styled-content style=\"fixed-case\">CGMS<\/jats:styled-content> analysis showed that <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content> patients had higher \u201clowest glucose\u201d level, and the incidence of hypoglycemic episodes was significantly lower compared with patients with normal <jats:styled-content style=\"fixed-case\">OGTT<\/jats:styled-content> result. In <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content> patients, glucose variability tended to be lower. Furthermore, in the whole patient cohort, glucose variability significantly decreased with time after transplantation. Summarizing, these novel data show that \u201clowest glucose\u201d level and hypoglycemic episodes are significantly influenced and altered in renal\u2010transplanted patients with <jats:styled-content style=\"fixed-case\">IGT<\/jats:styled-content>. Furthermore, there is a decrease in glucose variability with time after transplantation. The mechanism and relevance of these data need further investigations.<\/jats:p>","DOI":"10.1111\/petr.12106","type":"journal-article","created":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T11:16:27Z","timestamp":1372850187000},"page":"454-460","source":"Crossref","is-referenced-by-count":13,"title":["Continuous glucose monitoring system (<scp>CGMS<\/scp>) in kidney\u2010transplanted children"],"prefix":"10.1111","volume":"17","author":[{"given":"Krisztina","family":"Pasti","sequence":"first","affiliation":[{"name":"First Department of Pediatrics and Nephrology Research Laboratory of the Hungarian Academy of Sciences Semmelweis University Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila J.","family":"Szabo","sequence":"additional","affiliation":[{"name":"First Department of Pediatrics and Nephrology Research Laboratory of the Hungarian Academy of Sciences Semmelweis University Budapest 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