{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:59:43Z","timestamp":1781081983310,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T00:00:00Z","timestamp":1372809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PML<\/jats:styled-content> is a demyelinating disease of the central nervous system caused by infection with <jats:styled-content style=\"fixed-case\">JCV<\/jats:styled-content>. Several cases of <jats:styled-content style=\"fixed-case\">PML<\/jats:styled-content> in bone marrow and solid organ transplant recipients have been reported in recent years. <jats:styled-content style=\"fixed-case\">JCV<\/jats:styled-content> has been isolated from the gastrointestinal mucosa of immunocompromised patients, but there are no published reports of <jats:styled-content style=\"fixed-case\">PML<\/jats:styled-content> associated with symptomatic gastrointestinal involvement in kidney transplant recipients. We report a case of a nine\u2010yr\u2010old girl with a kidney transplant who developed a severe gastrointestinal illness causing pseudo\u2010obstruction in association with <jats:styled-content style=\"fixed-case\">PML<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">JCV<\/jats:styled-content> was suspected as the causative agent in this patient by the detection of high <jats:styled-content style=\"fixed-case\">JCV<\/jats:styled-content> titer through <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> analysis of the cerebrospinal fluid and blood and positive staining for simian virus 40 in the colon. <jats:styled-content style=\"fixed-case\">JCV<\/jats:styled-content> intestinal infection should be considered in kidney transplant recipients presenting with intestinal pseudo\u2010obstruction.<\/jats:p>","DOI":"10.1111\/petr.12107","type":"journal-article","created":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T11:16:27Z","timestamp":1372850187000},"source":"Crossref","is-referenced-by-count":5,"title":["Progressive multifocal leukoencephalopathy with gastrointestinal disease in a pediatric kidney transplant recipient"],"prefix":"10.1111","volume":"17","author":[{"given":"M. T.","family":"Burke","sequence":"first","affiliation":[{"name":"Department of Renal Medicine Nambour General Hospital Nambour Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Trnka","sequence":"additional","affiliation":[{"name":"Queensland Child and Adolescent Renal Service Royal Children's and Mater Children's Hospitals Brisbane Qld Australia"},{"name":"Department of Paediatrics and Child Health University of Queensland St Lucia Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Mater Children's Hospital South Brisbane Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Poole","sequence":"additional","affiliation":[{"name":"Department of Pathology Mater Hospital South Brisbane Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. J.","family":"McTaggart","sequence":"additional","affiliation":[{"name":"Queensland Child and Adolescent Renal Service Royal Children's and Mater Children's Hospitals Brisbane Qld Australia"},{"name":"Department of Paediatrics and Child Health University of Queensland St Lucia Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. R.","family":"Burke","sequence":"additional","affiliation":[{"name":"Queensland Child and Adolescent Renal Service Royal Children's and Mater Children's Hospitals Brisbane Qld Australia"},{"name":"Department of Paediatrics and Child Health University of Queensland St Lucia Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2010.00567.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1982.tb00254.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/597126"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02472-08"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2010.164"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-0986-y"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MP.0000044622.04245.A9"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858409356594"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/81.1.93"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00686650"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)91777-6"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00147-004-0779-3"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2010.01368.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31818b62c8"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.152512"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.4.1996-2001.2001"},{"key":"e_1_2_9_18_1","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1158\/1055-9965.2285.13.12","article-title":"Evidence for an association between JC virus and colorectal neoplasia","volume":"13","author":"Boland CR","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1158\/1055-9965.662.13.4","article-title":"No evidence of an association between JC virus and colorectal neoplasia","volume":"13","author":"Newcomb PA","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/13550280390195298"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1206559"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.2.253"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.187.1.8451420"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32830a5043"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001540"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181c0d4a1"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12107","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T22:40:32Z","timestamp":1696200032000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,3]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/petr.12107"],"URL":"https:\/\/doi.org\/10.1111\/petr.12107","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,3]]}}}