{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:13:39Z","timestamp":1791504819973,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T00:00:00Z","timestamp":1371427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>According to the 2008 World Health Organization classification, low\u2010grade lymphomas arising in transplant recipients are not considered as specific types of <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content>. Most such cases are not associated with <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content> infections, although rare reports of post\u2010transplant marginal zone lymphoma have been described. We describe the case of an 18\u2010yr\u2010old female with history of heart transplant who developed a breast mass, but was otherwise completely asymptomatic. Surgical excision of the mass and histopathologic examination showed a low\u2010grade <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\u2010cell lymphoma most consistent with marginal zone lymphoma with massive amyloid deposition; furthermore, numerous tumor cells were positive for <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content> by <jats:italic>in situ<\/jats:italic> hybridization for <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>\u2010encoded <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>. The patient was treated with reduction in immunosuppression, and no additional lesions developed. This case describes an atypical presentation of post\u2010transplant low\u2010grade <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\u2010cell lymphoma, unusual in its location, histopathologic features, and association with <jats:styled-content style=\"fixed-case\">EBV<\/jats:styled-content>, thereby adding to the rare previous accounts of such an entity, suggesting the need to include post\u2010transplant marginal zone lymphomas in the current classification of <jats:styled-content style=\"fixed-case\">PTLD<\/jats:styled-content>, and helping in determining the optimal treatment modalities for such tumors.<\/jats:p>","DOI":"10.1111\/petr.12111","type":"journal-article","created":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T08:20:46Z","timestamp":1371457246000},"source":"Crossref","is-referenced-by-count":16,"title":["<scp>EBV<\/scp>\u2010positive low\u2010grade marginal zone lymphoma in the breast with massive amyloid deposition arising in a heart transplant patient: A report of an unusual case"],"prefix":"10.1111","volume":"17","author":[{"given":"Samer","family":"Nassif","sequence":"first","affiliation":[{"name":"Department of Pathology Medstar Georgetown University Hospital Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metin","family":"Ozdemirli","sequence":"additional","affiliation":[{"name":"Department of Pathology Medstar Georgetown University Hospital Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,17]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"343","volume-title":"WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues","author":"Swerdlow SH","year":"2008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000040875.50963.2C"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1996.292338.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.10.109"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-008-3981-6"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21921"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182190999"},{"key":"e_1_2_10_9_1","first-page":"600","article-title":"Post\u2010transplant lymphoproliferative disorder: Extranodal marginal zone lymphoma occurring after renal transplantation","volume":"4","author":"Goldfarb JM","year":"2006","journal-title":"Clin Adv Hematol Oncol"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.1.74"},{"key":"e_1_2_10_11_1","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.5858\/2000-124-1233-PBMALT","article-title":"Primary bilateral mucosa\u2010associated lymphoid tissue lymphoma of the breast with atypical ductal hyperplasia and localized amyloidosis. A case report and review of the literature","volume":"124","author":"Gupta D","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200001000-00012"},{"key":"e_1_2_10_13_1","first-page":"964","article-title":"Post\u2010transplantation cutaneous B\u2010cell lymphoma with monoclonal Epstein\u2013Barr virus infection, responding to acyclovir and reduction in immunosuppression","volume":"16","author":"Mozzanica N","year":"1997","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2005.00363.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910301)67:5<1359::AID-CNCR2820670515>3.0.CO;2-4"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPI08WAKYVLHHA"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.167"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0761-8425(08)74983-0"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00136605"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2006.00408.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026134725003"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2002.96.2.0368"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.5732\/cjc.009.10627"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12111","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T15:35:03Z","timestamp":1696001703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,17]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1111\/petr.12111"],"URL":"https:\/\/doi.org\/10.1111\/petr.12111","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,17]]}}}