{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:21:27Z","timestamp":1779294087893,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T00:00:00Z","timestamp":1383782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T00:00:00Z","timestamp":1383782400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2014,2]]},"abstract":"Abstract<\/jats:title>\n \n Primary graft failure is the major cause of mortality in infant\n HT<\/jats:styled-content>\n x. The aim of this study was to characterize the indication and outcomes of infants requiring\n ECMO<\/jats:styled-content>\n support due to primary graft failure after\n HT<\/jats:styled-content>\n x. We performed a retrospective review of all infants (<1\u00a0yr) who underwent Htx from three institutions. From 1999 to 2008, 92 infants (<1\u00a0yr) received Htx. Sixteen children (17%) required\n ECMO<\/jats:styled-content>\n after Htx due to low cardiac output syndrome. Eleven (69%) infants were successfully weaned off\n ECMO<\/jats:styled-content>\n , and 9 (56%) infants were discharged with a mean follow\u2010up of 2.3\u00a0\u00b1\u00a02.5\u00a0yr. Mean duration of\n ECMO<\/jats:styled-content>\n in survivors was 5.4\u00a0days (2\u20137\u00a0days) compared with eight\u00a0days (2\u201310\u00a0days) in non\u2010survivors (p\u00a0=\u00a0\n NS<\/jats:styled-content>\n ). The five\u2010yr survival rate for all patients was 75%; however, the five\u2010yr survival rate was 40% in the\n ECMO<\/jats:styled-content>\n cohort vs. 80% in the non\u2010\n ECMO<\/jats:styled-content>\n cohort (p\u00a0=\u00a00.0001). Graft function within one\u00a0month post\u2010Htx was similar and normal between\n ECMO<\/jats:styled-content>\n and non\u2010\n ECMO<\/jats:styled-content>\n groups (shortening fraction\u00a0=\u00a042\u00a0\u00b1\u00a03 vs. 40\u00a0\u00b1\u00a02, p\u00a0=\u00a0\n NS<\/jats:styled-content>\n ). For infants,\n ECMO<\/jats:styled-content>\n support for primary graft failure had a lower short\u2010term and long\u2010term survival rate vs. non\u2010\n ECMO<\/jats:styled-content>\n patients. Duration of\n ECMO<\/jats:styled-content>\n did not adversely impact graft function and is an acceptable therapy for infants after\n HT<\/jats:styled-content>\n x for low cardiac output syndrome.\n <\/jats:p>","DOI":"10.1111\/petr.12181","type":"journal-article","created":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T08:44:42Z","timestamp":1383813882000},"page":"72-78","source":"Crossref","is-referenced-by-count":21,"title":["A multicenter study of primary graft failure after infant heart transplantation: Impact of extracorporeal membrane oxygenation on outcomes"],"prefix":"10.1111","volume":"18","author":[{"given":"S.","family":"Kaushal","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery University of Maryland Medical Center Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. L.","family":"Matthews","sequence":"additional","affiliation":[{"name":"Division of Cardiology Feinberg School of Medicine Northwestern University Ann and Robert H. Lurie Children's Hospital Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Division of Cardiology Arkansas Children's Hospital Little Rock AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Wehman","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery University of Maryland Medical Center Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Riddle","sequence":"additional","affiliation":[{"name":"Division of Cardiology St. Louis Children's Hospital St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Ying","sequence":"additional","affiliation":[{"name":"Division of Cardiology Feinberg School of Medicine Northwestern University Ann and Robert H. Lurie Children's Hospital Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Nubani","sequence":"additional","affiliation":[{"name":"Division of Cardiology Arkansas Children's Hospital Little Rock AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. E.","family":"Canter","sequence":"additional","affiliation":[{"name":"Division of Cardiology St. Louis Children's Hospital St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. R.","family":"Morrow","sequence":"additional","affiliation":[{"name":"Division of Cardiology Arkansas Children's Hospital Little Rock AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. B.","family":"Huddleston","sequence":"additional","affiliation":[{"name":"Cardiovascular\u2010Thoracic Surgery St. Louis Children's Hospital St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. L.","family":"Backer","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Feinberg School of Medicine Northwestern University Ann and Robert H. Lurie Children's Hospital Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Pahl","sequence":"additional","affiliation":[{"name":"Division of Cardiology Feinberg School of Medicine Northwestern University Ann and Robert H. Lurie Children's Hospital Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2008.06.016"},{"key":"e_1_2_7_3_1","first-page":"227","article-title":"Survival and risk factors for death after cardiac transplantation in infants: A multi\u2010institutional study. 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