{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:29:18Z","timestamp":1791178158923,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T00:00:00Z","timestamp":1387152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T00:00:00Z","timestamp":1387152000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To compare the incidence of acute histologically proven rejection in children who have had a liver transplant for hepatoblastoma with a control group of children transplanted for biliary atresia (\n                    <jats:styled-content style=\"fixed-case\">EHBA<\/jats:styled-content>\n                    ). A retrospective case notes based study was performed. Twenty patients were identified with hepatoblastoma who were transplanted at a single unit between 1991 and 2008. These were matched as closely as possible for age, gender, year of transplant and type of immunosuppression used to the control group transplanted for biliary atresia (n\u00a0=\u00a060). There was a significant decrease in rate of acute rejection as assessed by the rejection activity index (\n                    <jats:styled-content style=\"fixed-case\">RAI<\/jats:styled-content>\n                    ) in the hepatoblastoma group (75% vs. 50%, respectively, p\u00a0&lt;\u00a00.04). Chronic rejection was rare in both groups, but twice as common in the biliary atresia group. Equal levels of immunosuppression were achieved in both groups. Renal function was noted to be reduced one\u00a0yr post\u2010transplant in both groups, as previously reported. A modified immunosuppression regimen could be considered in children with hepatoblastoma undergoing liver transplantation.\n                  <\/jats:p>","DOI":"10.1111\/petr.12194","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T08:52:38Z","timestamp":1387183958000},"page":"52-57","source":"Crossref","is-referenced-by-count":16,"title":["Rejection is less common in children undergoing liver transplantation for hepatoblastoma"],"prefix":"10.1111","volume":"18","author":[{"given":"N. D.","family":"Ruth","sequence":"first","affiliation":[{"name":"Liver and Small bowel transplant Unit Birmingham Children's Hospital NHS Foundation Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Liver and Small bowel transplant Unit Birmingham Children's Hospital NHS Foundation Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Sharif","sequence":"additional","affiliation":[{"name":"Liver and Small bowel transplant Unit Birmingham Children's Hospital NHS Foundation Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Morland","sequence":"additional","affiliation":[{"name":"Department of Oncology Birmingham Children's Hospital NHS Foundation Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lloyd","sequence":"additional","affiliation":[{"name":"Liver and Small bowel transplant Unit Birmingham Children's Hospital NHS Foundation Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. J.","family":"McKiernan","sequence":"additional","affiliation":[{"name":"Liver and Small bowel transplant Unit Birmingham Children's Hospital NHS Foundation Trust Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950190310"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.22.3819"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.22.4857"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22876"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.51.11.875"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/hep.510250328","article-title":"Banff schema for grading liver allograft rejection: An international consensus document","volume":"25","author":"Demetris AJ","year":"2003","journal-title":"Hepatology"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.02.045"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2005.00354.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2012.11.006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.12.011"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.10376"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0022-3476(00)44469-0","article-title":"Liver transplantation and chemotherapy for hepatoblastoma and hepatocellular cancer in childhood and adolescence","volume":"36","author":"Reyes JD","year":"2000","journal-title":"J Paediatr"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.05.031"},{"key":"e_1_2_7_15_1","first-page":"270","article-title":"Renal function following liver transplantation for unresectable hepatoblastoma","volume":"7","author":"Lee W","year":"2003","journal-title":"Transplantation"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12194","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12194","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.12194","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:48:06Z","timestamp":1779252486000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,16]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/petr.12194"],"URL":"https:\/\/doi.org\/10.1111\/petr.12194","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,16]]}}}