{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T06:41:04Z","timestamp":1696056064608},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,12,28]],"date-time":"2013-12-28T00:00:00Z","timestamp":1388188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 15\u2010yr\u2010old boy presented with an anterior mediastinal mass, multiple lung metastases and obstruction of the left brachiocephalic vein, the superior vena cava and the subclavian vein. Tumor biopsy by <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> guidance confirmed a diagnosis of GCT. Five courses of <jats:styled-content style=\"fixed-case\">BEP<\/jats:styled-content> therapy were performed, and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> of the chest revealed reduction in the anterior mediastinal mass and disappearance of the multiple lung metastases. We performed the anterior mediastinal mass extraction followed by adjuvant chemotherapy consisting of <jats:styled-content style=\"fixed-case\">ICE<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>. However, the <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content> levels became elevated soon after. Abnormal accumulation was observed in the right upper lung by <jats:styled-content style=\"fixed-case\">DW<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. After the operation, two courses of <jats:styled-content style=\"fixed-case\">TI<\/jats:styled-content> chemotherapy and two courses of HDCT followed by auto\u2010PBSCT were performed. He was complicated with auditory disorder and renal dysfunction. Although HDCT followed by auto\u2010PBSCT was effective for the relapsed primary mediastinal GCT, a treatment strategy avoiding late complications is warranted.<\/jats:p>","DOI":"10.1111\/petr.12210","type":"journal-article","created":{"date-parts":[[2013,12,28]],"date-time":"2013-12-28T08:01:10Z","timestamp":1388217670000},"source":"Crossref","is-referenced-by-count":1,"title":["High\u2010dose chemotherapy followed by autologous peripheral blood stem cell transplantation for recurrent primary mediastinal malignant germ cell tumor: A case report"],"prefix":"10.1111","volume":"18","author":[{"given":"Dai","family":"Keino","sequence":"first","affiliation":[{"name":"Department of Pediatrics St. Marianna University School of Medicine Hospital Kanagawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensuke","family":"Kondoh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics St. Marianna University School of Medicine Hospital Kanagawa 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