{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:49:08Z","timestamp":1769042948859,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,4,12]],"date-time":"2014-04-12T00:00:00Z","timestamp":1397260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2014,6]]},"abstract":"Abstract<\/jats:title>CPM<\/jats:styled-content> is one of the most serious neurological complications that can occur after OLT<\/jats:styled-content> and is characterized by symmetrical demyelinization in the basis pontis. The etiology of CPM<\/jats:styled-content> remains unclear, although the rapid correction of the serum sodium and CNI<\/jats:styled-content> concentrations may be associated with the development of CPM<\/jats:styled-content>. With recent advances in MRI<\/jats:styled-content> technology, early diagnosis of CPM<\/jats:styled-content> has become possible. Here, we present the case of a five\u2010yr\u2010old female who developed CNI<\/jats:styled-content>\u2010associated CPM<\/jats:styled-content> after undergoing LDLT<\/jats:styled-content>. A decreased level of consciousness and dysphasia was noted one\u00a0wk after LDLT<\/jats:styled-content>, and MRI<\/jats:styled-content> revealed findings compatible with a diagnosis of CPM<\/jats:styled-content>. The patient fully recovered from the neurological deficits related to CPM<\/jats:styled-content> following the switch from the CNI<\/jats:styled-content> to sirolimus. We propose MRI<\/jats:styled-content> to be promptly considered for patients with abnormal neurological findings, together with the substitution of CNI<\/jats:styled-content> with an mTOR inhibitor as a management regimen for CNI<\/jats:styled-content>\u2010related CPM<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/petr.12255","type":"journal-article","created":{"date-parts":[[2014,4,12]],"date-time":"2014-04-12T07:13:43Z","timestamp":1397286823000},"source":"Crossref","is-referenced-by-count":11,"title":["Central pontine myelinolysis following pediatric living donor liver transplantation: A case report and review of literature"],"prefix":"10.1111","volume":"18","author":[{"given":"Hajime","family":"Uchida","sequence":"first","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seisuke","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kengo","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikumi","family":"Hamano","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanobu","family":"Shigeta","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kanazawa","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinari","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Nosaka","sequence":"additional","affiliation":[{"name":"Division of Radiology National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Kubota","sequence":"additional","affiliation":[{"name":"Division of Neurology National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mureo","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Transplantation Center National Center for Child Health and Development Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197803000-00003"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v10.i17.2540"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000120482"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.4.493"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.12659\/AOT.882008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000242426"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg061"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.44.11.909"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0387-7604(02)00013-X"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2011.01591.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)90452-7"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)01640-7"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000175124"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2006.00620.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm652"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2006.00381.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2000.19023"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2011.01560.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000144351.63740.81"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.02.101"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12255","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:31:53Z","timestamp":1695472313000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,12]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/petr.12255"],"URL":"https:\/\/doi.org\/10.1111\/petr.12255","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,12]]}}}