{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T19:35:44Z","timestamp":1769456144293,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,6,14]],"date-time":"2014-06-14T00:00:00Z","timestamp":1402704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2014,8]]},"abstract":"Abstract<\/jats:title>Although cardiac transplantation is life\u2010saving, morbidities from immunosuppression are significant. EoE<\/jats:styled-content> is a complication of calcineurin inhibitors following liver transplant causing feeding intolerance, weight loss, vomiting, and dysphagia. There are limited reports of EoE<\/jats:styled-content> following heart transplantation. We performed a retrospective single\u2010center review of pediatric cardiac transplant patients from 2000 to 2010. A case\u2013control analysis of patients with and without EoE<\/jats:styled-content> was performed evaluating heart transplantation outcomes such as rates of rejection, CAV<\/jats:styled-content>, PTLD<\/jats:styled-content>, and graft loss. Eighty\u2010six transplants were performed in 84 patients; 34 (40%) underwent diagnostic endoscopy, and 10 (12%) had EoE<\/jats:styled-content>. Median time to diagnosis of EoE<\/jats:styled-content> was 3.7\u00a0yr (IQR<\/jats:styled-content>: 2.0\u20135.2). There were no differences in demographics or use of induction medications between patients with or without EoE<\/jats:styled-content>. Patients with EoE<\/jats:styled-content> had fewer episodes of treated rejection (1.0 vs. 2.5; p\u00a0=\u00a00.04). Four of 10 (40%) EoE<\/jats:styled-content> patients had PTLD<\/jats:styled-content> compared with only 2\/24 (8%) of those without EoE<\/jats:styled-content> (p\u00a0=\u00a00.048; OR<\/jats:styled-content> 7.33 [95% CI<\/jats:styled-content>: 1.1\u201350.2]). There were no differences in CAV<\/jats:styled-content> or graft loss between groups. EoE<\/jats:styled-content> should be considered as a cause of GI<\/jats:styled-content> symptoms in children after cardiac transplantation and may be associated with fewer rejection episodes and increased rates of PTLD<\/jats:styled-content>, thus representing a marker of over\u2010immunosuppression.<\/jats:p>","DOI":"10.1111\/petr.12302","type":"journal-article","created":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T18:41:47Z","timestamp":1402944107000},"page":"491-496","source":"Crossref","is-referenced-by-count":11,"title":["Eosinophilic esophagitis in children following cardiac transplantation: Association with post\u2010transplant lymphoproliferative disorder and other transplant outcomes"],"prefix":"10.1111","volume":"18","author":[{"given":"Steven J.","family":"Kindel","sequence":"first","affiliation":[{"name":"Division of Cardiology Children's Hospital & Medical Center Omaha NE USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian F.","family":"Joy","sequence":"additional","affiliation":[{"name":"Division of Cardiology Nationwide Children's Hospital Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elfriede","family":"Pahl","sequence":"additional","affiliation":[{"name":"Division of Cardiology Ann and Robert H. Lurie Children's Hospital of Chicago Feinberg School of Medicine Northwestern University Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric L.","family":"Wald","sequence":"additional","affiliation":[{"name":"Divisions of Critical Care and Cardiology Ann and Robert H. Lurie Children's Hospital of Chicago Feinberg School of Medicine Northwestern University Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.08.001"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007040394"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2000.00112.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2006.10.011"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200101270-00015"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302X.2003.00086.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)67933-6"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(02)00383-2"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1989.01410080019002"},{"key":"e_1_2_9_11_1","first-page":"244","article-title":"Gastrointestinal complications and endoscopic findings in heart transplant patients","volume":"12","author":"Steck TB","year":"1993","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1397-3142.2003.00116.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2006.00538.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2008.01063.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.02.040"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2005.03.019"},{"issue":"1","key":"e_1_2_9_17_1","first-page":"2579","article-title":"Successful management of catastrophic intraabdominal complications following cardiac transplantation","volume":"21","author":"DiSesa VJ","year":"1989","journal-title":"Transplant Proc"},{"key":"e_1_2_9_18_1","first-page":"415","article-title":"Experience of FK506 immune suppression in pediatric heart transplantation: A study of long\u2010term adverse effects","volume":"15","author":"Asante\u2010Korang A","year":"1996","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200208270-00012"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2006.00542.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.agast960952"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8608886"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199404150-00010"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T23:12:01Z","timestamp":1695510721000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,14]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/petr.12302"],"URL":"https:\/\/doi.org\/10.1111\/petr.12302","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,14]]}}}