{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:35:40Z","timestamp":1777952140020,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,8,19]],"date-time":"2014-08-19T00:00:00Z","timestamp":1408406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Health","award":["5 T32 DK007662"],"award-info":[{"award-number":["5 T32 DK007662"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To describe the prevalence and outcomes of renal transplantation in children with <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> we performed a retrospective cohort analysis of all children receiving a first kidney\u2010alone transplant in the <jats:styled-content style=\"fixed-case\">UNOS<\/jats:styled-content> dataset from 2008 to 2011. Recipients with definite, probable, and without <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> were compared using chi\u2010square tests. Kaplan\u2013Meier curves were constructed for patient and graft survival. Cox proportional hazard models were used to estimate the association between <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> and graft failure and patient survival. Over the study period, 332 children with definite (117) or probable (215) <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> underwent first renal transplant, accounting for 16% of all first pediatric renal transplants (n\u00a0=\u00a02076). Children with definite <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> were not significantly different from children without <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> with respect to sex, ethnicity, or prevalence of acute rejection. <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> was associated with increased likelihood of deceased donor source. <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content> was not significantly associated with decreased graft or patient survival. In this first large\u2010scale study, up to 16% of first pediatric renal transplants were performed in children with <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content>. Short\u2010term graft and patient survival after transplant were equivalent between children with and without <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content>. Further research is needed to examine long\u2010term outcomes of transplant in this population.<\/jats:p>","DOI":"10.1111\/petr.12339","type":"journal-article","created":{"date-parts":[[2014,8,19]],"date-time":"2014-08-19T05:47:22Z","timestamp":1408427242000},"page":"714-719","source":"Crossref","is-referenced-by-count":37,"title":["Prevalence and outcomes of renal transplantation in children with intellectual disability"],"prefix":"10.1111","volume":"18","author":[{"given":"Aaron","family":"Wightman","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Pediatrics University of Wisconsin School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bessie","family":"Young","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Medicine VA Puget Sound Healthcare System Kidney Research Institute University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miranda","family":"Bradford","sequence":"additional","affiliation":[{"name":"Center for Clinical and Translational Research Seattle Children's Research Institute Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Dick","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Healey","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"McDonald","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Pediatrics University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodi","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Pediatrics University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,19]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"1","article-title":"Transplants and mental disability: The meaning of discrimination","volume":"6","author":"Veatch RM","year":"2001","journal-title":"Ethics Intellect Disabil"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01994023"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(93)71865-4"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V611"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2008.01072.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2006.00545.x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq105"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v31.pm9506689"},{"key":"e_1_2_12_10_1","first-page":"211","article-title":"Renal transplantation in Down syndrome: A report of the North American Pediatric Renal Transplant Cooperative Study","volume":"2","author":"Baqi N","year":"1998","journal-title":"Pediatr Transplant"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.11.015"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470258019"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12339","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:17:19Z","timestamp":1695475039000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,19]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/petr.12339"],"URL":"https:\/\/doi.org\/10.1111\/petr.12339","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,19]]}}}