{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:58:32Z","timestamp":1792180712219,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T00:00:00Z","timestamp":1414368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mechanical circulatory support has been used for more than 30\u00a0yr to allow the heart to recover from ischemia and injury. There are limited pediatric data, however, on the efficacy of <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> in the setting of post\u2010transplantation support for primary graft dysfunction or rejection. Data from all patients at our university\u2010affiliated, tertiary care children's hospital who underwent <jats:styled-content style=\"fixed-case\">OHT<\/jats:styled-content> between 1998 and 2010 and required subsequent <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> support were analyzed. The primary outcome measure was survival to hospital discharge. Two hundred and three pediatric patients underwent <jats:styled-content style=\"fixed-case\">OHT<\/jats:styled-content> between 1998 and 2010 at our institution. Twenty\u2010nine of these patients experienced post\u2010transplantation cardiac failure requiring <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> support, 18 of whom survived to hospital discharge (62%). Survival in the rejection and allograft vasculopathy group was 75%, and survival in patients with primary graft failure was 53% after <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> support (p\u00a0=\u00a00.273). Patient survival to hospital discharge was not associated with ischemic time or duration of <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> provides hemodynamic support in the setting of cardiac failure and can be used successfully after pediatric <jats:styled-content style=\"fixed-case\">OHT<\/jats:styled-content> for primary graft dysfunction or rejection.<\/jats:p>","DOI":"10.1111\/petr.12382","type":"journal-article","created":{"date-parts":[[2014,10,27]],"date-time":"2014-10-27T09:13:39Z","timestamp":1414401219000},"page":"68-75","source":"Crossref","is-referenced-by-count":20,"title":["Extracorporeal membrane oxygenation support after pediatric orthotopic heart transplantation"],"prefix":"10.1111","volume":"19","author":[{"given":"Jennifer A.","family":"Su","sequence":"first","affiliation":[{"name":"Department of Pediatrics Mattel Children's Hospital UCLA Los Angeles CA 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C.","family":"Alejos","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Pediatrics Mattel Children's Hospital UCLA and David Geffen School of Medicine at UCLA Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.180449"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(68)90173-2"},{"key":"e_1_2_9_4_1","first-page":"II60","article-title":"Extracorporeal membrane oxygenation support as a bridge to pediatric heart transplantation","volume":"90","author":"Nido PJ","year":"1994","journal-title":"Circulation"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(99)70333-8"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0022-5223(19)36471-2","article-title":"Extracorporeal membrane 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