{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:36:36Z","timestamp":1761510996563},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T00:00:00Z","timestamp":1429142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content> related to <jats:styled-content style=\"fixed-case\">BK<\/jats:styled-content> virus replication might be a severe complication following allogeneic HSCT. There are no clearly defined treatment guidelines in pediatric population. The data on the effectiveness of ICI to manage severe bleeding in children are very limited. We report our experience of intravesical cidofovir in four children, 6\u201315\u00a0yr of age, to manage grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\u2013<jats:styled-content style=\"fixed-case\">IV BK<\/jats:styled-content> virus\u2010associated <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>. Three of four children had high CSA serum level prior to developing cystitis. Intravesical instillations of cidofovir resulted only in temporal relief of bleeding. After immune suppression was withdrawn or tapered, intravesical instillations of formalin solution had to be undertaken to abort severe bleeding. We concluded that intravesical cidofovir alone did not appear to be sufficiently effective in case of severe <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>, necessitating complimentary procedures to stop macrohematuria.<\/jats:p>","DOI":"10.1111\/petr.12477","type":"journal-article","created":{"date-parts":[[2015,4,17]],"date-time":"2015-04-17T05:15:20Z","timestamp":1429247720000},"source":"Crossref","is-referenced-by-count":18,"title":["Intravesical cidofovir to treat BK virus\u2010associated hemorrhagic cystitis in children after hematopoietic stem cell transplantation"],"prefix":"10.1111","volume":"19","author":[{"given":"Jelena","family":"Rascon","sequence":"first","affiliation":[{"name":"Center of Pediatric Oncology and Hematology Bone Marrow Transplantation unit Children's Hospital Affiliate of Vilnius University Hospital Santariskiu Klinikos Vilnius Lithuania"},{"name":"Vilnius University Vilnius Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilvydas","family":"Verkauskas","sequence":"additional","affiliation":[{"name":"Vilnius University Vilnius Lithuania"},{"name":"Department of Pediatric Urology Children's Hospital Affiliate of Vilnius University Hospital Santariskiu Klinikos Vilnius Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramune","family":"Pasauliene","sequence":"additional","affiliation":[{"name":"Center of Pediatric Oncology and Hematology Bone Marrow Transplantation unit Children's Hospital Affiliate of Vilnius University Hospital Santariskiu Klinikos Vilnius Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vytautas","family":"Zubka","sequence":"additional","affiliation":[{"name":"Center of Pediatric Anesthesiology and Intensive Care Children's Hospital Affiliate of Vilnius University Hospital Santariskiu Klinikos Vilnius 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