{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T12:31:54Z","timestamp":1763641914332},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T00:00:00Z","timestamp":1430352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rituximab (anti\u2010B CD20 ab.) in recently widely used in renal transplantation. Case history: A 10\u2010yr\u2010old patient with end\u2010stage renal failure due to multidrug\u2010resistant <jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content> was transplanted with renal graft from deceased donor and presented immediate recurrence of <jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> was started on day 3 and patient received <jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> pulses, however with no effect. Rituximab (4\u00a0\u00d7\u00a0375\u00a0mg\/m<jats:sup>2<\/jats:sup>) was administered. Chest radiographs taken at that time were normal. Partial remission was achieved and the patient was discharged in good condition. Sequential recurrence appeared two\u00a0wk afterward. Twelve sessions of <jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content> were performed and six pulses of <jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> were given, effecting a partial remission. Three months after the last dose of rituximab, patient was admitted with increasing respiratory failure, requiring mechanical ventilation. Infectious background, including <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> BKV<\/jats:styled-content>, mycoplasma, and pneumocystis, was not confirmed. The patient was treated with <jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content> pulses, <jats:styled-content style=\"fixed-case\">IVIG<\/jats:styled-content>, and a variety of antibiotics. Ground\u2010glass opacity was confirmed on lung <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> images. Respiratory failure worsened, despite aggressive ventilation and patient passed away after three\u00a0wk at ICU. A destruction of alveolar epithelium and extended pulmonary fibrosis was confirmed in the autopsy report. The case represents a fatal <jats:styled-content style=\"fixed-case\">RALI<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/petr.12481","type":"journal-article","created":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T11:20:00Z","timestamp":1430392800000},"source":"Crossref","is-referenced-by-count":10,"title":["Fatal rituximab\u2010associated lung injury syndrome in a patient treated with rituximab for recurrence of post\u2010transplant nephrotic syndrome"],"prefix":"10.1111","volume":"19","author":[{"given":"Ryszard","family":"Grenda","sequence":"first","affiliation":[{"name":"Department of Nephrology, Kidney Transplantation and Hypertension The Children's Memorial Health Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wioletta","family":"Jarmu\u017cek","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Kidney Transplantation and Hypertension The Children's Memorial Health Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Rubik","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Kidney Transplantation and Hypertension The Children's Memorial Health Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Migda\u0142","sequence":"additional","affiliation":[{"name":"Intensive Care Unit Department of Anesthesiology and Intensive Care The Children's Memorial Health Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Pronicki","sequence":"additional","affiliation":[{"name":"Department of Pathology The Children's Memorial Health Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008538"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182977ab1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2004030172"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604043341402"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2010.01068.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2006.00395.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181aed9d7"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2010.01303.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181a6bac5"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ker290"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2013030251"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.09421010"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60541-9"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0814-1"},{"key":"e_1_2_6_16_1","first-page":"1","article-title":"Biologics in renal transplantation","volume":"26062963","author":"Grenda R","year":"2014","journal-title":"Pediatr Nephrol"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.211"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.2005.25.8.1151"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02499.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20864"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-009-1195-9"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.4065\/79.7.949"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20910"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200306263482619"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080209"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdi232"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1532\/IJH97.04163"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2803-z"},{"key":"e_1_2_6_29_1","first-page":"111","article-title":"Addition of rituximab to cyclophosphamide, doxorubicin, vincristine and prednisolone therapy has a high risk of developing interstitial pneumonia in patients with non\u2010Hodgkin lymphoma","volume":"22","author":"Katsuya S","year":"2008","journal-title":"Ann Nucl Med"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2010.25.1.86"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2011.06.060"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2007.01102.x"},{"key":"e_1_2_6_33_1","first-page":"274","article-title":"Clinical aspects of plasmapheresis therapy in children \u2013 experience with six hundred sessions","volume":"18","author":"Rubik J","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.thj.6200133"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-13-39"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.3.791"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.9.2771"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200306263482620"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12481","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T13:57:48Z","timestamp":1696168668000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,30]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/petr.12481"],"URL":"https:\/\/doi.org\/10.1111\/petr.12481","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,30]]}}}