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The <jats:styled-content style=\"fixed-case\">HIT<\/jats:styled-content> clinical sequelae of thrombocytopenia and thrombosis are secondary to the activation of platelets by heparin\u2013antibody complexes. Diagnosis involves clinical observations and confirmatory laboratory testing using antibody detection and the functional <jats:styled-content style=\"fixed-case\">SRA<\/jats:styled-content>. As we describe in the following case of a six\u2010yr\u2010old female, the <jats:styled-content style=\"fixed-case\">SRA<\/jats:styled-content> may be difficult to interpret in the case of high\u2010titer antibodies and illustrates the need for repeat testing in cases of high clinical suspicion.<\/jats:p>","DOI":"10.1111\/petr.12540","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T11:11:37Z","timestamp":1434625897000},"source":"Crossref","is-referenced-by-count":2,"title":["Challenging diagnosis and treatment of <scp>HIT<\/scp> in child with ventricular assistance device"],"prefix":"10.1111","volume":"19","author":[{"given":"Lauren","family":"Weintraub","sequence":"first","affiliation":[{"name":"Division of Hematology\/Oncology Department of Pediatrics Children's Hospital at Montefiore Albert Einstein College of Medicine Bronx NY 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