{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:39:39Z","timestamp":1784194779061,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,7,6]],"date-time":"2015-07-06T00:00:00Z","timestamp":1436140800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2015,9]]},"abstract":"Abstract<\/jats:title>Reactivation of HSV<\/jats:styled-content> and VZV<\/jats:styled-content> is common following HSCT<\/jats:styled-content>. Consensus guidelines do not support the use of routine screening for viremia following HSCT<\/jats:styled-content> in adults, but no such clear guidelines exist in pediatrics. In our center, routine practice was to screen patients weekly for HSV<\/jats:styled-content> and VZV<\/jats:styled-content> viremia until engraftment in autologous transplant patients and up to day +100 in allogeneic transplant patients. We conducted a retrospective study of over 500 patients to establish whether this screening identified any patients with HSV<\/jats:styled-content> or VZV<\/jats:styled-content> viremia who would not have been identified by clinical signs or symptoms. Over a 4.5\u2010yr period, routine screening identified three cases of HSV<\/jats:styled-content> viremia and one case of VZV<\/jats:styled-content> viremia. Two patients had persistent, unexplained fever and two patients had skin or mucosal lesions suggestive of HSV<\/jats:styled-content>\/VZV<\/jats:styled-content>. We conclude that routine screening for HSV<\/jats:styled-content> and VZV<\/jats:styled-content> viremia in pediatric HSCT<\/jats:styled-content> patients has a very low yield and that viremia can be reliably identified by targeted testing in patients with vesicular skin lesions, oral or genital ulceration, unexplained fever, neurological symptoms, or unexplained abnormal liver transaminases.<\/jats:p>","DOI":"10.1111\/petr.12551","type":"journal-article","created":{"date-parts":[[2015,7,6]],"date-time":"2015-07-06T12:20:51Z","timestamp":1436185251000},"page":"640-644","source":"Crossref","is-referenced-by-count":8,"title":["The yield of monitoring for HSV<\/scp> and VZV<\/scp> viremia in pediatric hematopoietic stem cell transplant patients"],"prefix":"10.1111","volume":"19","author":[{"given":"Katharine","family":"Patrick","sequence":"first","affiliation":[{"name":"Division of Hematology\/Oncology The Hospital for Sick Children Toronto ON 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