{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:45:10Z","timestamp":1790660710807,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,8,29]],"date-time":"2015-08-29T00:00:00Z","timestamp":1440806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Digestive Health Center Biostatistical Core"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Kidney transplantation is the optimal treatment of ESRD in children. Some studies have reported inferior outcomes in recipients of <jats:styled-content style=\"fixed-case\">LDN<\/jats:styled-content> allografts who are \u22645\u00a0yr of age. We performed a retrospective review of pediatric recipient outcomes of 110 <jats:styled-content style=\"fixed-case\">LDN<\/jats:styled-content> allografts at our institution and examined predictors of adverse outcomes. Subgroup analysis was performed by dividing recipients into three age categories: 0\u20135\u00a0yr, 6\u201317\u00a0yr, and \u226518\u00a0yr. There was no significant difference between incidences of <jats:styled-content style=\"fixed-case\">DGF<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">ARE<\/jats:styled-content> between groups. Kaplan\u2013Meier analysis demonstrated 100% allograft survival in 0\u2010 to 5\u2010yr\u2010old recipients, nearly reaching statistical significance (p\u00a0=\u00a00.07) for outcome superior to that of the two older age groups. Pretransplant HD was associated with increased risk of <jats:styled-content style=\"fixed-case\">DGF<\/jats:styled-content> (p\u00a0=\u00a00.05). Significant risk factors for <jats:styled-content style=\"fixed-case\">ARE<\/jats:styled-content> were recipient weight &gt;15\u00a0kg (p\u00a0=\u00a00.033) and multiple renal arteries (p\u00a0=\u00a00.047). Previous <jats:styled-content style=\"fixed-case\">ARE<\/jats:styled-content> was associated with an increased risk of allograft failure (p\u00a0=\u00a00.02). <jats:styled-content style=\"fixed-case\">LDN<\/jats:styled-content> is not associated with increased risk of <jats:styled-content style=\"fixed-case\">DGF<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> ARE<\/jats:styled-content>, or allograft failure in the youngest recipients. These findings support an aggressive pursuit of preemptive transplantation even in the youngest pediatric allograft recipients.<\/jats:p>","DOI":"10.1111\/petr.12587","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T12:42:47Z","timestamp":1441197767000},"page":"836-843","source":"Crossref","is-referenced-by-count":5,"title":["Laparoscopic donor nephrectomy for the pediatric recipient population: Risk factors for adverse outcomes"],"prefix":"10.1111","volume":"19","author":[{"given":"Ashley E.","family":"Walther","sequence":"first","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail C.","family":"Coots","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens W.","family":"Goebel","sequence":"additional","affiliation":[{"name":"Division of Nephrology Cincinnati Children's Hospital Medical Center Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria H.","family":"Alonso","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick C.","family":"Ryckman","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg M.","family":"Tiao","sequence":"additional","affiliation":[{"name":"Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center Cincinnati OH 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