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The other major indication for combined transplantation is <jats:styled-content style=\"fixed-case\">ARPKD<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> appears to be superior to sequential liver and kidney transplantation in the majority of patients and overall results following <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> are now good, even in small children. Clinical observations suggest that there is an immunological advantage of <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> in comparison with isolated liver or kidney transplantation. More clinical studies are necessary to identify the best candidates for <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> while the availability of donor organs is low.<\/jats:p>","DOI":"10.1111\/petr.12593","type":"journal-article","created":{"date-parts":[[2015,9,10]],"date-time":"2015-09-10T14:19:19Z","timestamp":1441894759000},"page":"820-826","source":"Crossref","is-referenced-by-count":16,"title":["Review of combined liver and kidney transplantation in children"],"prefix":"10.1111","volume":"19","author":[{"given":"Rainer","family":"Ganschow","sequence":"first","affiliation":[{"name":"Department of Pediatrics University Medical Center Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Hoppe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University Medical Center Bonn 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