{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:36:04Z","timestamp":1790832964938,"version":"4.1.0"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T00:00:00Z","timestamp":1452038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005744","name":"Lastentautien Tutkimuss\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005744","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008723","name":"Suomen L\u00e4\u00e4ketieteen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008723","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Suomen Akatemia","doi-asserted-by":"publisher","award":["1122539"],"award-info":[{"award-number":["1122539"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Timely and reliable detection of viruses is of key importance in early diagnosis of infection(s) following allogeneic <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>. Among the immunocompetent, infections with <jats:styled-content style=\"fixed-case\">BKP<\/jats:styled-content>y<jats:styled-content style=\"fixed-case\">V<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">JCPyV<\/jats:styled-content> are mostly subclinical, while post\u2010<jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>, the former may cause <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content> and the latter <jats:styled-content style=\"fixed-case\">PML<\/jats:styled-content>. The epidemiology and clinical impact of the newly identified <jats:styled-content style=\"fixed-case\">KIPyV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> WUPyV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> MCPyV<\/jats:styled-content>, and TSPyV in this context remain to be defined. To assess the incidence and clinical impact of <jats:styled-content style=\"fixed-case\">BKPyV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> JCPyV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> KIPyV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> WUPyV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> MCPyV<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">TSPyV<\/jats:styled-content> infections, we performed longitudinal molecular surveillance for <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>emias of these <jats:styled-content style=\"fixed-case\">HPyV<\/jats:styled-content>s among 53 pediatric <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> recipients. Surveillance pre\u2010<jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> and for three months post\u2010<jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> revealed <jats:styled-content style=\"fixed-case\">BKPyV DNA<\/jats:styled-content>emia in 20 (38%) patients. Our data demonstrate frequent <jats:styled-content style=\"fixed-case\">BKPyV DNA<\/jats:styled-content>emia among pediatric patients with <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> and the confinement of clinical symptoms to high copy numbers alone. <jats:styled-content style=\"fixed-case\">MCPyV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">JCPyV<\/jats:styled-content> viremias occurred at low and <jats:styled-content style=\"fixed-case\">TSPyV<\/jats:styled-content> viremia at very low prevalences. <jats:styled-content style=\"fixed-case\">KIPyV<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">WUPyV<\/jats:styled-content> viremias were not demonstrable in this group of immunocompromised patients.<\/jats:p>","DOI":"10.1111\/petr.12659","type":"journal-article","created":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T07:34:46Z","timestamp":1452065686000},"page":"424-431","source":"Crossref","is-referenced-by-count":10,"title":["Polyomaviruses <scp>BK<\/scp>,<scp> JC<\/scp>,<scp> KI<\/scp>,<scp> WU<\/scp>,<scp> MC<\/scp>, and <scp>TS<\/scp> in children with allogeneic hematopoietic stem cell transplantation"],"prefix":"10.1111","volume":"20","author":[{"given":"Jaana","family":"Rahiala","sequence":"first","affiliation":[{"name":"Division of Hematology\u2010Oncology and Stem Cell Transplantation Children's Hospital University of Helsinki Helsinki Finland"},{"name":"Department of Pediatrics Porvoo Hospital Porvoo Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minna","family":"Koskenvuo","sequence":"additional","affiliation":[{"name":"Division of Hematology\u2010Oncology and Stem Cell Transplantation Children's Hospital University of Helsinki Helsinki Finland"},{"name":"Department of Pediatrics Turku University Hospital Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadreza","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Department of Virology University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Waris","sequence":"additional","affiliation":[{"name":"Division of Microbiology and Genetics Department of Clinical Virology Turku University Hospital Turku Finland"},{"name":"Department of Virology University of Turku Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tytti","family":"Vuorinen","sequence":"additional","affiliation":[{"name":"Division of Microbiology and Genetics Department of Clinical Virology Turku University Hospital Turku Finland"},{"name":"Department of Virology University of Turku Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maija","family":"Lappalainen","sequence":"additional","affiliation":[{"name":"Department of Virology and Immunology Helsinki University Hospital Laboratory Services (HUSLAB) Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla","family":"Saarinen\u2010Pihkala","sequence":"additional","affiliation":[{"name":"Division of Hematology\u2010Oncology and Stem Cell Transplantation Children's Hospital University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Allander","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"S\u00f6derlund\u2010Venermo","sequence":"additional","affiliation":[{"name":"Department of Virology University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Hedman","sequence":"additional","affiliation":[{"name":"Department of Virology University of Helsinki Helsinki Finland"},{"name":"Department of Virology and Immunology Helsinki University Hospital Laboratory Services (HUSLAB) Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olli","family":"Ruuskanen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Turku University Hospital Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Vettenranta","sequence":"additional","affiliation":[{"name":"Division of Hematology\u2010Oncology and Stem Cell Transplantation Children's Hospital University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,1,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)91776-4"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)91777-6"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10450"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/597126"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2011.02.012"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-12-4988"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1083-8791(03)00269-6"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1107829"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00028-07"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030064"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1152586"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001024"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir614"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-215"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199204093261504"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2013.11.008"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-12-383"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-7-251"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2007.09.008"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2009.04.008"},{"key":"e_1_2_8_22_1","first-page":"288","article-title":"Primary BK virus (BKV) infection due to possible BKV transmission during bone marrow transplantation is not the major cause of hemorrhagic cystitis in transplanted children","volume":"2","author":"Bogdanovic G","year":"1998","journal-title":"Pediatr Transplant"},{"key":"e_1_2_8_23_1","first-page":"405","article-title":"Prevalence of viral infections and hemorrhagic cystitis in hematopoietic stem cell transplant recipients","volume":"9","author":"Shakiba E","year":"2011","journal-title":"Exp Clin Transplant"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2013.05.002"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2012.09.003"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705909"},{"key":"e_1_2_8_27_1","first-page":"939","article-title":"Full myeloablative conditioning and an unrelated HLA mismatched donor increase the risk for BK virus\u2010positive hemorrhagic cystitis in allogeneic hematopoetic stem cell transplanted patients","volume":"31","author":"Dalianis T","year":"2011","journal-title":"Anticancer Res"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1086\/511863"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/158.3.563"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2011.01505.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1086\/599829"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00974-10"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2005.06.007"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1179\/1607845412Y.0000000010"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1810.120359"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2010.06.017"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.22222"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062764"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2004.131015"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1501.080758"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1086\/596062"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1810.120477"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2011.05.024"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2009.05.002"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12659","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T23:02:09Z","timestamp":1696201329000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,6]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/petr.12659"],"URL":"https:\/\/doi.org\/10.1111\/petr.12659","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,6]]}}}