{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T09:01:33Z","timestamp":1726131693455},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,2,21]],"date-time":"2016-02-21T00:00:00Z","timestamp":1456012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intra\u2010operative arterial vasospasm during pediatric renal transplantation is an urgent clinical situation resulting in end\u2010organ ischemia, associated changes in parenchymal turgor and color, diminished flow on ultrasound, and if left untreated, allograft loss. We hypothesized that intra\u2010operative intra\u2010arterial injection of nitroglycerin would reverse vasospasm and improve renal perfusion. A three\u2010yr\u2010old girl with end\u2010stage renal disease due to autosomal recessive polycystic kidney disease on peritoneal dialysis underwent deceased donor renal transplantation. After optimal immediate reperfusion and hemodynamic parameters, the kidney lost turgor and became mottled in appearance despite adequate hilar arterial and venous Doppler waveforms. Two aliquots of 40 \u03bcg (0.4 mL of a 100 \u03bcg\/mL) nitroglycerin solution were injected directly into the renal artery 10 min apart. Nitroglycerin resulted in dramatic change in the consistency and appearance of the allograft. An improvement in renal blood flow was demonstrated by ultrasound after the second intra\u2010arterial nitroglycerin injection with only a transient decrease in systemic arterial blood pressure. The child experienced normal allograft perfusion on serial postoperative ultrasounds, with a prompt decrease in serum creatinine and excellent diuresis. Intra\u2010arterial nitroglycerin is a promising option for intra\u2010operative arterial vasospasm during pediatric renal transplantation with objective improvement in blood flow and perfusion.<\/jats:p>","DOI":"10.1111\/petr.12688","type":"journal-article","created":{"date-parts":[[2016,2,22]],"date-time":"2016-02-22T05:10:19Z","timestamp":1456117819000},"page":"463-466","source":"Crossref","is-referenced-by-count":5,"title":["Intra\u2010arterial nitroglycerin for intra\u2010operative arterial vasospasm during pediatric renal transplantation"],"prefix":"10.1111","volume":"20","author":[{"given":"Frank J.","family":"Penna","sequence":"first","affiliation":[{"name":"Division of Paediatric Urology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Harvey","sequence":"additional","affiliation":[{"name":"Division of Nephrology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"John","sequence":"additional","affiliation":[{"name":"Division of Radiology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Division of Radiology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Luginbuehl","sequence":"additional","affiliation":[{"name":"Division of Anesthesia The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakan I.","family":"Odeh","sequence":"additional","affiliation":[{"name":"Division of Paediatric Urology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahad","family":"Alyami","sequence":"additional","affiliation":[{"name":"Division of Paediatric Urology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin A.","family":"Koyle","sequence":"additional","affiliation":[{"name":"Division of Paediatric Urology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando J.","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"Division of Paediatric Urology The Hospital for Sick Children and University of Toronto Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1027441"},{"key":"e_1_2_8_3_1","first-page":"35","article-title":"Intraoperative hemodynamics in the recipients of kidney allografts from living related donors","volume":"1","author":"Belorusov OS","year":"1995","journal-title":"Urol Nefrol (Mosk)"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000235967"},{"key":"e_1_2_8_5_1","first-page":"256","article-title":"A comparative study on the effect of lidocaine and furosemide on urinary output and graft function after renal transplantation","volume":"1","author":"Razzaghi MR","year":"2004","journal-title":"Urol J"},{"key":"e_1_2_8_6_1","first-page":"469","article-title":"Coronary artery spasm during angiography in a pediatric heart transplant recipient: Subsequent prevention by intracoronary nitroglycerin 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