{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:33:36Z","timestamp":1792074816279,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,3,27]],"date-time":"2016-03-27T00:00:00Z","timestamp":1459036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purposes of this study were to analyze the effects of an <jats:styled-content style=\"fixed-case\">ERS<\/jats:styled-content> on time to transplantation and to describe our center's experience with <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>. Patients who received <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> between 2000 and 2013 were included. Patient and allograft characteristics, chemotherapy regimens, and prior surgical therapies were examined. The interval between diagnosis and <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> prior to and following the institution of an <jats:styled-content style=\"fixed-case\">ERS<\/jats:styled-content> for transplant was compared. Survival and tumor recurrence were analyzed. Nineteen patients received <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> for <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> (mean age 33 months). All children received grafts from deceased donors. Two patients underwent prior resections. Tumor recurred in four patients (21.1%). Both patients who received salvage transplants experienced post\u2010<jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> recurrence. Three of the four recurrences occurred in spite of adjuvant chemotherapy. There were three deaths: two from metastatic disease. One\u2010 and five\u2010yr survivals were 86.1% and 73.8%. After the institution of the <jats:styled-content style=\"fixed-case\">ERS<\/jats:styled-content>, the mean interval between tissue diagnosis and <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> was significantly reduced. Our series of 19 patients demonstrates a 21% recurrence of <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> following <jats:styled-content style=\"fixed-case\">OLT<\/jats:styled-content> despite chemotherapy. Five\u2010yr survival reached 73.8%. A system of early referral can effectively reduce times between diagnosis and transplant.<\/jats:p>","DOI":"10.1111\/petr.12699","type":"journal-article","created":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T04:52:42Z","timestamp":1459140762000},"page":"515-522","source":"Crossref","is-referenced-by-count":18,"title":["Effects of an early referral system on liver transplantation for hepatoblastoma at Texas Children's Hospital"],"prefix":"10.1111","volume":"20","author":[{"given":"Michael","family":"Kueht","sequence":"first","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplantation Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Oncology Texas Children's Hospital Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Rana","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplantation Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Cotton","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplantation Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"O'Mahony","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplantation Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Goss","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplantation Baylor College of Medicine Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199102000-00004"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2012.11.006"},{"key":"e_1_2_9_4_1","first-page":"12093","article-title":"Liver transplantation in the management of unresectable hepatoblastoma in children","volume":"4","author":"Meyers RL","year":"2012","journal-title":"Front Biosci (Elite Ed)"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2005.02.004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.10376"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.05.031"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200209150-00011"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2003.10.072"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21586"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24038"},{"key":"e_1_2_9_12_1","unstructured":"The Organ Procurement and Transplantation Network.Pediatric and Liver & Intestinal Organ Transplantation Committees. 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