{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T11:33:46Z","timestamp":1774265626578,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,7,8]],"date-time":"2016-07-08T00:00:00Z","timestamp":1467936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Moyamoya disease is a chronic cerebrovascular disorder with progressive stenosis. We describe a four\u2010yr\u2010old female with features of moyamoya disease referred to our center for kidney transplant evaluation with <jats:styled-content style=\"fixed-case\">ESRD<\/jats:styled-content> secondary to presumed renal dysplasia along with concern for cerebral vascular anomalies. With her constellation of organ involvement, a genetic workup revealed a homozygous, frameshift mutation in the mitochondrial methionyl\u2010tRNA formyltransferase gene. Given her vascular anomalies and evidence of prior infarcts seen on cerebral imaging, it was felt that her risk of future stroke events was high and that hypotension or intravascular volume depletion would further exacerbate this risk. In hopes of improving her tenuous cerebral perfusion, she underwent a bilateral temporal craniotomy for superficial temporal artery to middle cerebral artery bypass. We highlight the challenges faced in a child with ESRD and kidney transplantation when cerebral vasculature is compromised. A multidisciplinary approach is critical in determining the need for a revascularization procedure prior to transplant and to help reduce the risk of ischemic or hemorrhagic events in this patient population.<\/jats:p>","DOI":"10.1111\/petr.12758","type":"journal-article","created":{"date-parts":[[2016,7,9]],"date-time":"2016-07-09T04:44:26Z","timestamp":1468039466000},"page":"1000-1003","source":"Crossref","is-referenced-by-count":7,"title":["Challenges managing end\u2010stage renal disease and kidney transplantation in a child with MTFMT mutation and moyamoya disease"],"prefix":"10.1111","volume":"20","author":[{"given":"Aris","family":"Oates","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Pediatrics University of California, San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Brennan","sequence":"additional","affiliation":[{"name":"Division of Transplant Department of Surgery University of California, San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Slavotinek","sequence":"additional","affiliation":[{"name":"Division of Genetics University of California, San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Alsadah","sequence":"additional","affiliation":[{"name":"Division of Genetics University of California, San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging University of California, San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marsha M.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Pediatrics University of California, San Francisco San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1982.tb13707.x"},{"key":"e_1_2_8_3_1","first-page":"37","article-title":"Hypogenesis of bilateral internal carotid artery","volume":"9","author":"Takeuchi K","year":"1957","journal-title":"Shinkei"},{"key":"e_1_2_8_4_1","first-page":"49","article-title":"Moyamoya disease and syndromes: From genetics to clinical management","volume":"8","author":"Guey S","year":"2015","journal-title":"Appl Clin Genet"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5853\/jos.2015.01627"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1964.206.1.25"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.166575"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2348-0548.130399"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000228543"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03080707"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00101.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000371902"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-011-1926-6"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12758","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T17:41:58Z","timestamp":1696182118000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,8]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/petr.12758"],"URL":"https:\/\/doi.org\/10.1111\/petr.12758","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,8]]}}}