{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T13:50:57Z","timestamp":1764251457496,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,25]],"date-time":"2016-12-25T00:00:00Z","timestamp":1482624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,3]]},"abstract":"Abstract<\/jats:title>TS of immunosuppression is a rare, disfiguring dermatologic condition caused by TS<\/jats:styled-content>\u2010associated polyomavirus in immunosuppressed patients. It is difficult to treat, with no clearly described approach to resolve the condition completely and safely. We report a child with a renal transplant who developed TS<\/jats:styled-content> and was treated with significant reduction in immunosuppression and transient use of cidofovir cream. The combined approach, primarily with significant long\u2010term reduction in immunosuppression guided by monitoring BK<\/jats:styled-content> viremia in our patient, led to complete resolution of TS<\/jats:styled-content> without recurrence or graft rejection by 5\u00a0years after transplant. This outcome was superior to all other reports of TS<\/jats:styled-content> in children after transplantation. Closely monitoring for BK<\/jats:styled-content> viremia, as a surrogate marker of over\u2010immunosuppression, can guide adjustment in immunosuppressant medication to treat polyomavirus disease without developing the complication of graft rejection in a patient at significant risk.<\/jats:p>","DOI":"10.1111\/petr.12849","type":"journal-article","created":{"date-parts":[[2016,12,26]],"date-time":"2016-12-26T04:06:50Z","timestamp":1482725210000},"source":"Crossref","is-referenced-by-count":18,"title":["Complete resolution of trichodysplasia spinulosa in a pediatric renal transplant patient: Case report and literature review"],"prefix":"10.1111","volume":"21","author":[{"given":"Lauren P.","family":"Coogle","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Pediatrics Medical College of Wisconsin Milwaukee WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen E.","family":"Holland","sequence":"additional","affiliation":[{"name":"Division of Pediatric Dermatology Department of Dermatology Medical College of Wisconsin Milwaukee WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Pan","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Pediatrics Medical College of Wisconsin Milwaukee WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott K.","family":"Van Why","sequence":"additional","affiliation":[{"name":"Division of Nephrology Department of Pediatrics Medical College of Wisconsin Milwaukee WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsp.5640227"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001024"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05391.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.175"},{"key":"e_1_2_6_6_1","first-page":"770","article-title":"The trichodysplasia spinulosa\u2010associated polyomavirus: virological background and clinical implications","volume":"121","author":"Kazem S","year":"2013","journal-title":"Acta Path Micro IM"},{"key":"e_1_2_6_7_1","first-page":"1355","article-title":"Seroprevalence of trichodysplasia spinulosa\u2010associated polyomavirus","volume":"17","author":"Meijden E","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2010.01664.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318282ba83"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000149691.83086.dc"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(03)01490-7"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2010.01278.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-0953"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02952.x"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12849","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12849","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T12:31:40Z","timestamp":1695040300000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,25]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/petr.12849"],"URL":"https:\/\/doi.org\/10.1111\/petr.12849","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"type":"print","value":"1397-3142"},{"type":"electronic","value":"1399-3046"}],"subject":[],"published":{"date-parts":[[2016,12,25]]},"article-number":"e12849"}}