{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:37:00Z","timestamp":1761511020037,"version":"3.41.2"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T00:00:00Z","timestamp":1487116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>While reduced <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> following isolated organ transplantation has been previously reported, there are no data in the context of children following <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content>. Twenty\u2010three children who underwent <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> at our institution were included in the study. The indication for <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> was <jats:styled-content style=\"fixed-case\">PH<\/jats:styled-content>1 in 13 patients and <jats:styled-content style=\"fixed-case\">ARPKD<\/jats:styled-content> in 10 patients. Quantification of <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> was facilitated through the use of the Peds<jats:styled-content style=\"fixed-case\">QL<\/jats:styled-content> 4.0 Generic Core Scale. The results of the study were compared to healthy children and published data of children who had undergone <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>x or <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>x. The <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content> samples' child self\u2010report showed good <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content>. No statistically significant difference was found between the patients with <jats:styled-content style=\"fixed-case\">PH<\/jats:styled-content>1 and patients with <jats:styled-content style=\"fixed-case\">ARPKD<\/jats:styled-content> (<jats:italic>P<\/jats:italic>=.4). Compared to healthy children, a significant difference in the total scale score, the physical health score, and the school functioning was reported. <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> did not differ significantly when compared to patients following isolated <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>x or <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>x. To improve <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">CLKT<\/jats:styled-content>, a focus on patients' physical health, educational performances, and overall quality of life is crucial. Thus, coordinated medical care across disciplines and psychological and social support is essential to achieve this goal.<\/jats:p>","DOI":"10.1111\/petr.12902","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T04:02:44Z","timestamp":1487217764000},"source":"Crossref","is-referenced-by-count":7,"title":["Health\u2010related quality of life after combined liver and kidney transplantation in children"],"prefix":"10.1111","volume":"21","author":[{"given":"Kaja","family":"Schmaeschke","sequence":"first","affiliation":[{"name":"Pediatric Gastroenterology and Hepatology University Children's Hospital University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Lezius","sequence":"additional","affiliation":[{"name":"Department of Medical Biometry and Epidemiology University Medical Center Hamburg\u2010Eppendorf  Hamburg 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