{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T09:00:35Z","timestamp":1773910835741,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,4,9]],"date-time":"2017-04-09T00:00:00Z","timestamp":1491696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Standard management of intra\u2010abdominal pediatric solid tumors requires complete resection. However, tumors with multiple organ and vascular involvement present a unique surgical challenge. We conducted a retrospective chart review of four patients, aged 2\u201014\u00a0years, undergoing MVT for intra\u2010abdominal tumors with significant involvement of the visceral arteries and\/or portomesenteric venous system at our institution. Indications for MVT included hepatocellular carcinoma, inflammatory myofibroblastic tumor, and two cases of hepatoblastoma. Grafts included liver, stomach, small bowel, and pancreas in all patients, with two patients also receiving spleens, and one, a partial esophageal transplant. Median hospital stay was 80\u00a0days. Postoperative complications included reoperation for abdominal hematoma and bowel obstruction, steroid responsive intestinal rejection, wound dehiscence, fungemia, seizures, and chyle leak with pleural effusion. One patient developed Epstein\u2010Barr virus\u2010associated complications which responded well to treatment. On follow\u2010up (range 2.8\u20107.8\u00a0years), all patients have satisfactory graft function and no evidence of recurrent disease. MVT is an effective means of achieving complete gross resection of intra\u2010abdominal malignancies in patients with multiple organ and vascular involvement.<\/jats:p>","DOI":"10.1111\/petr.12904","type":"journal-article","created":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T04:17:12Z","timestamp":1491797832000},"source":"Crossref","is-referenced-by-count":12,"title":["Multivisceral transplantation for abdominal tumors in children: A single center experience and review of the literature"],"prefix":"10.1111","volume":"21","author":[{"given":"Eliza","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Surgery Boston Children's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Hodgkinson","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima","family":"Fawaz","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, &amp; Nutrition Boston Children's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khashayar","family":"Vakili","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heung Bae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital and Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.10376"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2012.11.006"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21654"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2007.00751.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(96)90148-7"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12623"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-013-0822-9"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2003.50155"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1001\/jama.1989.03420100085029","article-title":"Transplantation of multiple abdominal viscera","volume":"261","author":"Starzl TE","year":"1989","journal-title":"JAMA"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-2047-7"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2013.09.002"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(00)02593-8"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21056"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(99)00775-7"},{"key":"e_1_2_9_16_1","first-page":"545","article-title":"Multivisceral transplantation","volume":"57","author":"Margreiter R","year":"2005","journal-title":"Chir Ital"},{"key":"e_1_2_9_17_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1399-0012.1990.tb00204.x","article-title":"Treatment of upper abdominal malignancies with organ cluster procedures","volume":"4","author":"Mieles L","year":"1990","journal-title":"Clin Transplant"},{"key":"e_1_2_9_18_1","first-page":"1","article-title":"Assessment of five\u2010year experience with abdominal organ cluster transplantation","volume":"180","author":"Alessiani M","year":"1995","journal-title":"J Am Coll Surg"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-015-3852-3"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.12.067"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2015.1847"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1007056"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.23970"},{"key":"e_1_2_9_24_1","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/01.sla.0000183347.61361.7a","article-title":"100 multivisceral transplants at a single center","volume":"242","author":"Tzakis AG","year":"2005","journal-title":"Ann Surg"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b67725"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.12904","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.12904","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T21:35:43Z","timestamp":1750196143000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.12904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,9]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1111\/petr.12904"],"URL":"https:\/\/doi.org\/10.1111\/petr.12904","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"value":"1397-3142","type":"print"},{"value":"1399-3046","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,9]]},"article-number":"e12904"}}