{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:23:56Z","timestamp":1787869436641,"version":"build-2784847793"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,5]],"date-time":"2017-03-05T00:00:00Z","timestamp":1488672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["PP00P3_139021"],"award-info":[{"award-number":["PP00P3_139021"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Split\u2010liver transplantation (<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>) allows transplantation of two recipients from one deceased donor, thereby increasing pool of grafts. However, split <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> may be hampered by technical problems, and split grafts are still considered suboptimal organs in some centres. We analysed the outcomes in split\u2010 and whole\u2010liver recipients in a combined adult\u2010to\u2010paediatric transplantation programme. Records of paediatric and adult patients having undergone <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> from 1999 to 2013 were analysed retrospectively. All splits were performed in situ. Adult split\u2010graft recipients were matched 1:2 with whole\u2010graft recipients (matching criteria: <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> MELD<\/jats:styled-content>, year of transplantation, age), and matched to the paediatric recipient transplanted from the same donor. Post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> complications were classified according to the Clavien scale. Among children, 32 split\u2010 and 31 whole\u2010graft recipients were analysed. Among adults, 20 split\u2010 and 40 matched whole\u2010graft recipients were analysed. In both populations, the post\u2010operative complications did not differ between split\u2010 and whole\u2010graft recipients. There was no difference in 1\u2010year graft and patient survival between split\u2010 and whole\u2010graft recipients in paediatric (90% vs. 97%, 94% vs. 97%, respectively) and in adult recipients (89% in both, 89% vs. 92%, respectively). In the analysis of both recipients issued from the same donor, there was no association in the prevalence and severity of complications. A case\u2010by\u2010case analysis showed that split mortality was unrelated to <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> in all but one patient (small\u2010for\u2010size left split graft). In the setting of careful donor selection, recipient matching and surgical skill, in situ split <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> is an effective and safe technique to increase the number of available organs, and split livers should no longer considered marginal grafts.<\/jats:p>","DOI":"10.1111\/petr.12908","type":"journal-article","created":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T04:22:51Z","timestamp":1488774171000},"source":"Crossref","is-referenced-by-count":39,"title":["Early complications after liver transplantation in children and adults: Are split grafts equal to each other and equal to whole livers?"],"prefix":"10.1111","volume":"21","author":[{"given":"Dehlia","family":"Moussaoui","sequence":"first","affiliation":[{"name":"Division of Paediatric Surgery University Centre of Paediatric Surgery of Western Switzerland University Hospitals of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Toso","sequence":"additional","affiliation":[{"name":"Divisions of Transplantation and Visceral Surgery University Hospitals of Geneva  Geneva Switzerland"},{"name":"Hepato\u2010Pancreato\u2010Biliary Centre University Hospitals of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Nowacka","sequence":"additional","affiliation":[{"name":"Division of Paediatric Surgery University Centre of Paediatric Surgery of Western Switzerland University Hospitals of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie A.","family":"McLin","sequence":"additional","affiliation":[{"name":"Division of Paediatric Gastroenterology University Hospitals of Geneva  Geneva 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Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Majno","sequence":"additional","affiliation":[{"name":"Divisions of Transplantation and Visceral Surgery University Hospitals of Geneva  Geneva Switzerland"},{"name":"Hepato\u2010Pancreato\u2010Biliary Centre University Hospitals of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara E.","family":"Wildhaber","sequence":"additional","affiliation":[{"name":"Division of Paediatric Surgery University Centre of Paediatric Surgery of Western Switzerland University Hospitals of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,5]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2006.11.006"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03587.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13197"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02172.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02443.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01262776"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800760723"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000146148.01586.72"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.03.003"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21745"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21563"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6135.2004.00403.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199504270-00001"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3180caa415"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31827da6c9"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24015"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2011.218"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181c5cdc1"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23667"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199401000-00007"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2007.00737.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12363"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23910"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21849"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.01.023"},{"issue":"672","key":"e_1_2_9_28_1","first-page":"e1","article-title":"Deceased\u2010donor 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