{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:31:03Z","timestamp":1761823863097,"version":"3.41.2"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,11]],"date-time":"2017-03-11T00:00:00Z","timestamp":1489190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005795","name":"Chang Gung Memorial Hospital, Linkou","doi-asserted-by":"publisher","award":["CORPG3C0201"],"award-info":[{"award-number":["CORPG3C0201"]}],"id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Gastric carcinoid tumor is rarely diagnosed in children. We report a case of gastric carcinoid tumor that occurred after allogeneic <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>. A 13\u2010year\u2010old girl with ETP acute lymphoblastic leukemia underwent allogeneic <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> from a 7\/8 <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010matched unrelated donor. She presented with rashes, abdominal pain, and diarrhea, which were suggestive of <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content>, 7\u00a0months after <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>. Immunosuppressive agents failed to resolve these symptoms well. After a series of evaluations, carcinoid syndrome caused by a gastric carcinoid tumor was diagnosed. The tumor was located in the antral region and resulted in partial gastric outlet obstruction. She received subtotal gastrectomy with regional lymph node dissection. However, she had a flare\u2010up of <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> 1\u00a0month after surgery, and immunosuppressive therapy was intensified accordingly. Although her <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> was getting better, she developed respiratory syncytial viral pneumonia with rapid progression to respiratory failure. She died of multiple organ failure 2\u00a0months postoperatively. This is the first pediatric case of a gastric carcinoid tumor following allogeneic <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content>. Our case also highlights the necessity for pediatric transplant physicians to be aware of carcinoid syndrome caused by this rare tumor in the setting of <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> with poor response to immunosuppressive agents.<\/jats:p>","DOI":"10.1111\/petr.12911","type":"journal-article","created":{"date-parts":[[2017,3,11]],"date-time":"2017-03-11T11:07:07Z","timestamp":1489230427000},"source":"Crossref","is-referenced-by-count":3,"title":["Development of a gastric carcinoid tumor following allogeneic hematopoietic stem cell transplantation for early T\u2010cell precursor acute lymphoblastic leukemia"],"prefix":"10.1111","volume":"21","author":[{"given":"Tsung\u2010Yen","family":"Chang","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin\u2010Yao","family":"Lai","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao\u2010Jan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih\u2010Yen","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tang\u2010Her","family":"Jaing","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuen","family":"Hsueh","sequence":"additional","affiliation":[{"name":"Department of Pathology Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee\u2010Yung","family":"Shih","sequence":"additional","affiliation":[{"name":"Division of Hematology\u2010Oncology Department of Internal Medicine Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih\u2010Hsiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology Chang Gung Memorial Hospital Chang Gung University College of Medicine  Taoyuan 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