{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:32:02Z","timestamp":1763037122433,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,8,19]],"date-time":"2017-08-19T00:00:00Z","timestamp":1503100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Acute <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> is a rare complication after liver transplantation that has a high mortality rate. We experienced an infant case complicated with acute <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content>. An 8\u2010month\u2010old infant with biliary atresia underwent <jats:styled-content style=\"fixed-case\">LDLT<\/jats:styled-content> with a graft obtained from his mother. Their <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>s showed a donor\u2010dominant one\u2010way match, not at <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">DR<\/jats:styled-content> but at <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010A, <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010B, and <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010C (recipient; A 31\/33, B 51\/54, C 1\/14, <jats:styled-content style=\"fixed-case\">DR<\/jats:styled-content> 9\/11, donor; A 31\/\u2010, B 51\/\u2010, C 14\/\u2010, <jats:styled-content style=\"fixed-case\">DR<\/jats:styled-content> 8\/11). The patient exhibited a high fever, skin rash, and diarrhea, and was diagnosed with acute <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> based on the blood chimerism test. Despite immunosuppression treatment with prednisolone and tacrolimus, plasma exchange, blood transfusion including cord blood transplantation, and antibiotics, the child died on postoperative day 126. Donor\u2010dominant one\u2010way matching at <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content> class 1 can be a high\u2010risk factor for acute <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> despite <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content> class 2 mismatching.<\/jats:p>","DOI":"10.1111\/petr.13039","type":"journal-article","created":{"date-parts":[[2017,8,20]],"date-time":"2017-08-20T03:52:49Z","timestamp":1503201169000},"source":"Crossref","is-referenced-by-count":11,"title":["Fatal graft\u2010versus\u2010host disease after living\u2010donor liver transplantation from an HLA\u2010DR\u2010mismatched donor"],"prefix":"10.1111","volume":"21","author":[{"given":"Keita","family":"Shimata","sequence":"first","affiliation":[{"name":"Department of Transplantation and Pediatric Surgery Kumamoto University Hospital  Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rieko","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kumamoto University Hospital  Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Anan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kumamoto University Hospital  Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koushi","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Transplantation and Pediatric Surgery Kumamoto University Hospital  Kumamoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Transplantation and Pediatric Surgery Kumamoto University Hospital  Kumamoto 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