{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:38:09Z","timestamp":1790026689595,"version":"4.0.1"},"reference-count":53,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T00:00:00Z","timestamp":1503446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">GS<\/jats:styled-content>2 is a rare autosomal recessive disease characterized by hypopigmentation, variable immunodeficiency with <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> is the only curative treatment for <jats:styled-content style=\"fixed-case\">GS<\/jats:styled-content>2. We analyzed the outcome of 10 children with <jats:styled-content style=\"fixed-case\">GS<\/jats:styled-content>2 who underwent <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> at our center between October 1997 and September 2013. The median age of the patients at transplant was 13.5\u00a0months (range, 6\u201058\u00a0months). All of the patients developed <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content> before <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> and received <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content> 94 or <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content> 2004 protocols. Donors were <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010identical relatives in 8 patients, <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010mismatched relatives in 2 patients. Engraftment was achieved in all except one patient. None of the patients developed acute <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content>. Chronic <jats:styled-content style=\"fixed-case\">GVHD<\/jats:styled-content> occurred in one and veno\u2010occlusive disease occurred in four patients. Eight of the patients are under remission without any neurologic sequelae\u2014median time of disease\u2010free survival is 92.4\u00a0months. The present study shows successful transplant outcome without long\u2010term neurologic sequelae in patients with <jats:styled-content style=\"fixed-case\">GS<\/jats:styled-content>2 who underwent <jats:styled-content style=\"fixed-case\">HSCT<\/jats:styled-content> from <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010related donors.<\/jats:p>","DOI":"10.1111\/petr.13040","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T03:36:47Z","timestamp":1503545807000},"source":"Crossref","is-referenced-by-count":15,"title":["Hematopoietic stem cell transplantation in children with Griscelli syndrome: A single\u2010center experience"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1207-4205","authenticated-orcid":false,"given":"Baris","family":"Kuskonmaz","sequence":"first","affiliation":[{"name":"Division of Bone Marrow Transplantation Department of Pediatrics Hacettepe University Faculty of 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