{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:43:54Z","timestamp":1753879434631,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,9,7]],"date-time":"2017-09-07T00:00:00Z","timestamp":1504742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2017,12]]},"abstract":"Abstract<\/jats:title>CMV<\/jats:styled-content> infection plays an important role in the postoperative course following solid organ transplantation. We present the case of an 11\u2010year\u2010old male patient who underwent LDLT<\/jats:styled-content> due to severe hepatopulmonary syndrome and biliary cirrhosis. Four weeks after LDLT<\/jats:styled-content>, he developed persistent GI<\/jats:styled-content> bleeding and was subjected to repeated endoscopic treatment and radiological arterial embolization to stop the bleeding from duodenal ulcers. Diagnostic workup was negative for CMV<\/jats:styled-content> disease. Because the bleeding persisted, surgical treatment was indicated, and a pancreas\u2010preserving duodenectomy was performed. Immunohistochemical staining of the surgical specimen demonstrated diffuse endothelial infiltration by CMV<\/jats:styled-content>. Despite ganciclovir treatment, the patient developed new erosions in the jejunal mucosa and melena; ganciclovir was discontinued, and foscarnet was started, resulting in clinical improvement and the cessation of bleeding. This case highlights the technical aspects of performing a complex upper GI<\/jats:styled-content> resection in a patient recently subjected to LDLT<\/jats:styled-content>, taking care to avoid injury to the previous liver graft anastomosis and restore GI<\/jats:styled-content> continuity. Moreover, CMV<\/jats:styled-content> tissue\u2010invasive disease compartmentalized in the GI<\/jats:styled-content> tract may be difficult to diagnose, as indicated by the negative results of antigenemia and PCR<\/jats:styled-content> assays and endoscopic superficial mucosal biopsies.<\/jats:p>","DOI":"10.1111\/petr.13059","type":"journal-article","created":{"date-parts":[[2017,9,7]],"date-time":"2017-09-07T18:26:02Z","timestamp":1504808762000},"source":"Crossref","is-referenced-by-count":2,"title":["Pancreas\u2010preserving duodenectomy after living donor liver transplantation for invasive cytomegalovirus disease"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8716-3467","authenticated-orcid":false,"given":"Rodrigo","family":"Vincenzi","sequence":"first","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo A.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Chapchap","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel C. C.","family":"Machado","sequence":"additional","affiliation":[{"name":"Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7908-8268","authenticated-orcid":false,"given":"Karina M. O.","family":"Roda","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helry L.","family":"Candido","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcel R.","family":"Benavides","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A.","family":"D'Assuncao","sequence":"additional","affiliation":[{"name":"Gastrointestinal Endoscopy Unit Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rogerio C.","family":"Afonso","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Plinio","family":"Turine","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7928-1479","authenticated-orcid":false,"given":"Fernando P.","family":"Marson","sequence":"additional","affiliation":[{"name":"Gastrointestinal Endoscopy Unit Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Seda","family":"Neto","sequence":"additional","affiliation":[{"name":"Hepatology and Liver Transplantation Hospital Sirio\u2010Libanes Sao Paulo SP Brazil"},{"name":"A.C. Camargo Cancer Center Sao Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12103"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2013.45.3.260"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12755"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21932"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(05)80198-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2007.08.061"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-011-0382-9"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-014-3331-z"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit521"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.4081\/idr.2014.5512"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.13059","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13059","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T22:29:04Z","timestamp":1695508144000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.13059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,7]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/petr.13059"],"URL":"https:\/\/doi.org\/10.1111\/petr.13059","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"type":"print","value":"1397-3142"},{"type":"electronic","value":"1399-3046"}],"subject":[],"published":{"date-parts":[[2017,9,7]]},"article-number":"e13059"}}