{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T08:17:35Z","timestamp":1782548255102,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,12]],"date-time":"2017-11-12T00:00:00Z","timestamp":1510444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>LT exerts considerable stress on the heart perioperatively. Limited data exist on impact of cardiovascular diseases on <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> children. This study evaluated the outcomes of children with <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> who underwent <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> and compared with pretransplant findings. From 518 <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> recipients, 82 (15.8%) had <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>. Sixty patients were classified as low\u2010risk adjustment for congenital heart surgery 1 (<jats:styled-content style=\"fixed-case\">RACHS<\/jats:styled-content> 1 and 2). Five patients were classified as <jats:styled-content style=\"fixed-case\">RACHS<\/jats:styled-content> \u22653. The most common echocardiographic finding in the <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> patients (25\/82) was <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> patients had more abnormal <jats:styled-content style=\"fixed-case\">EKG<\/jats:styled-content> (32.4% vs 14.5%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), abnormal chest X\u2010ray (11.8% vs 1.4%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001), and altered echocardiography (89.7% vs 15.4%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) findings compared with the No\u2010<jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> group pretransplant. Post\u2010transplant, significant differences between groups were observed related to abnormal <jats:styled-content style=\"fixed-case\">EKG<\/jats:styled-content> (14.7% vs 7.0%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03) and echocardiography (48.5% vs 3.2%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.01) findings. Pretransplant <jats:styled-content style=\"fixed-case\">ASD<\/jats:styled-content> spontaneously closed in 22 patients. At 1 and 5\u00a0years post\u2010transplant, there was no difference in the survival rate between groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.96). The prevalence of <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> in recipients of <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> was high, and its presence was associated with significantly higher cardiac decompensation before and after <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>. Minor and moderate cardiovascular disease did not impact the long\u2010term survival.<\/jats:p>","DOI":"10.1111\/petr.13081","type":"journal-article","created":{"date-parts":[[2017,11,13]],"date-time":"2017-11-13T04:06:36Z","timestamp":1510545996000},"source":"Crossref","is-referenced-by-count":5,"title":["Outcomes of liver transplantation in pediatric recipients with cardiovascular disease"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6417-1744","authenticated-orcid":false,"given":"M\u00e1rcio Miranda","family":"Brito","sequence":"first","affiliation":[{"name":"Hospital Sirio\u2010Libanes  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao","family":"Seda Neto","sequence":"additional","affiliation":[{"name":"Hospital Sirio\u2010Libanes  Sao Paulo SP Brazil"},{"name":"A. C. Camargo Cancer Center  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo A.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Hospital Sirio\u2010Libanes  Sao Paulo SP Brazil"},{"name":"A. C. Camargo Cancer Center  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Pugliese","sequence":"additional","affiliation":[{"name":"Hospital Sirio\u2010Libanes  Sao Paulo SP Brazil"},{"name":"A. C. Camargo Cancer Center  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera B.","family":"Danesi","sequence":"additional","affiliation":[{"name":"Hospital Sirio\u2010Libanes  Sao Paulo SP Brazil"},{"name":"A. C. Camargo Cancer Center  Sao Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helry L.","family":"Candido","sequence":"additional","affiliation":[{"name":"Hospital Sirio\u2010Libanes  Sao Paulo SP Brazil"},{"name":"A. 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