{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:44:43Z","timestamp":1793378683621,"version":"4.5.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,1,17]],"date-time":"2018-01-17T00:00:00Z","timestamp":1516147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>LT has contributed to an elevation in cure rates for patients with unresectable HB; however, patients with recurrent <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> have poor prognosis. To analyze the prognostic and therapeutic factors that influence the clinical outcome of patients with <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> receiving <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>, we retrospectively analyzed 24 patients with <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> who underwent <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> between 1997 and 2015. The 5\u2010year OS rate of all patients was 69.6\u00b19.7%. The 5\u2010year <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> rate of 11 patients receiving salvage <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> for recurrent tumor after a primary resection was comparable to that of 13 patients receiving primary <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>. Among 12 evaluable patients receiving primary <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>, six of 10 patients with a decline of serum <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content> &gt;95% at <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> are currently alive and in remission, whereas two patients with a decline of <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content> \u226495% experienced post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> relapse. Among 9 evaluable patients receiving salvage <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>, all three patients with any decline of <jats:styled-content style=\"fixed-case\">AFP<\/jats:styled-content> at <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> are currently alive in remission, and three of six patients with no response to pre\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> salvage chemotherapy are also alive and in remission. Response to chemotherapy may be a reliable marker for prediction of post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> relapse, even for patients receiving salvage <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/petr.13113","type":"journal-article","created":{"date-parts":[[2018,1,17]],"date-time":"2018-01-17T07:05:20Z","timestamp":1516172720000},"source":"Crossref","is-referenced-by-count":28,"title":["Prognostic and therapeutic factors influencing the clinical outcome of hepatoblastoma after liver transplantation: A single\u2010institute experience"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6844-2011","authenticated-orcid":false,"given":"Katsutsugu","family":"Umeda","sequence":"first","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine Kyoto University  Kyoto 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