{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:13:00Z","timestamp":1787771580362,"version":"build-2784847793"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Early signs of subclinical <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content> dysfunction can be detected by ultrasound for <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content>. Although A\u2010A are at high risk for <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content> disease, <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> of A\u2010A kidney transplant recipients has not been previously investigated. The aim of this prospective, controlled, longitudinal study was to investigate determinants of <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> in a multiracial pediatric kidney transplant population, with a focus on A\u2010A. Transplant recipients (n\u00a0=\u00a042) had <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, waist\u2010to\u2010height ratio, fasting glucose, lipid panel, HbA1c%, and <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> measured at 1, 18, and 30 months post\u2010transplant. Twenty\u2010four healthy children (14 A\u2010A) served as controls. <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> of A\u2010A transplant (0.49, 0.49, and 0.48 mm) was higher than non\u2010<jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content> transplant (0.43, 0.44, and 0.44 mm) at 1, 18, and 30 months and higher than A\u2010A controls (0.47 mm). Hyperparathyroidism prior to transplant predicted high <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content>\u2010for\u2010race. A\u2010A race was associated with 10% higher <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> vs non\u2010A\u2010A transplant. Metabolic syndrome was associated with 0.03\u00a0\u00b1\u00a00.01\u00a0mm increase in <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> among A\u2010A transplant recipients only. In conclusion, A\u2010A kidney transplant recipients have increased <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content>. Metabolic syndrome disproportionately affects <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content> of A\u2010A children post\u2010transplant. Identification of subclinical <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content> damage, detected by <jats:styled-content style=\"fixed-case\">CIMT<\/jats:styled-content>, may provide an opportunity for early detection of <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content> risk in this vulnerable population.<\/jats:p>","DOI":"10.1111\/petr.13163","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T07:36:38Z","timestamp":1518075398000},"source":"Crossref","is-referenced-by-count":4,"title":["Increased carotid intima\u2010media thickness in African American pediatric kidney transplant recipients"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0795-3210","authenticated-orcid":false,"given":"Kristen","family":"Sgambat","sequence":"first","affiliation":[{"name":"Department of Nephrology Children's National Health System  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Clauss","sequence":"additional","affiliation":[{"name":"Department of Cardiology Children's National Health System  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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