{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:02:42Z","timestamp":1788397362367,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:00:00Z","timestamp":1523836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Despite continued advancements in perioperative care for pediatric liver transplant (LT), graft\u2010threatening vascular occlusion events including hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) remain a source of significant morbidity and mortality. Perioperative anticoagulation is commonly used for the prevention of\n                    <jats:styled-content style=\"fixed-case\">HAT<\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">PVT<\/jats:styled-content>\n                    , but evidence\u2010based guidelines are lacking. The goals of this survey were to determine the frequency of use of an anticoagulation protocol and to describe variation in anticoagulation practices among pediatric LT centers. The study consisted of an online survey distributed to members of\n                    <jats:styled-content style=\"fixed-case\">SPLIT<\/jats:styled-content>\n                    . The survey focused on institutional anticoagulation practices employed to reduce the incidence of graft and life\u2010threatening vascular occlusion events. Responses were received from 31 of 39\n                    <jats:styled-content style=\"fixed-case\">SPLIT<\/jats:styled-content>\n                    centers. All respondents report using anticoagulation after pediatric\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    , and approximately 90% have institutional anticoagulation protocols. Subgroup analysis of high volume pediatric\n                    <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>\n                    centers revealed similar variability in anticoagulation patterns. All participating\n                    <jats:styled-content style=\"fixed-case\">SPLIT<\/jats:styled-content>\n                    centers reported the use of post\u2010transplant anticoagulation and nearly all use a protocol. However, there is marked variability in the type and dose of anticoagulation as well as the timing of initiation and duration of therapy across centers.\n                  <\/jats:p>","DOI":"10.1111\/petr.13193","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T22:33:31Z","timestamp":1523918011000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Perioperative anticoagulation practices for pediatric liver transplantation"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2800-7848","authenticated-orcid":false,"given":"Stylianos","family":"Voulgarelis","sequence":"first","affiliation":[{"name":"Divisions of Pediatric and Adult Cardiac Anesthesiology Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Vitola","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacee M.","family":"Lerret","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Transplant Surgery Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny C.","family":"Hong","sequence":"additional","affiliation":[{"name":"Division of Transplant Surgery Department of Surgery Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Scott","sequence":"additional","affiliation":[{"name":"Divisions of Pediatric Anesthesiology and Pediatric Critical Care Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"},{"name":"Pediatric Liver Transplant Anesthesia Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"},{"name":"Pediatric Intensive Care Unit Medical College of Wisconsin Children's Hospital of Wisconsin  Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12268"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2301"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/hq0701.093686"},{"key":"e_1_2_10_5_1","volume-title":"Pharmacology","author":"Brenner GM","year":"2013"},{"key":"e_1_2_10_6_1","volume-title":"Pharmacology: Lippincott's Illustrated Reviews","author":"Whalen 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