{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:39:45Z","timestamp":1792175985702,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T00:00:00Z","timestamp":1528675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    HB is the most common primary liver tumor in children. Complete tumor excision, either by partial resection or by total hepatectomy and liver transplantation, in combination with chemotherapy provides the best chance for cure. We performed a retrospective analysis of patients who underwent liver transplantation for HB and herein present our 14\u2010year single\u2010institution experience. Twenty\u2010five patients underwent liver transplantation for\n                    <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>\n                    at a median age of 26\u00a0months (\n                    <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                    : 15\u201044). Graft survival was 96%, 87%, and 80% at 1, 3, and 5\u00a0years, respectively. There were four patient deaths, three of them due to disease recurrence within the first year post\u2010transplant. Ten\u2010year overall survival was 84%. Three recipients initially presented with pulmonary metastases and underwent resection of metastatic disease, of which two are alive at 3.9\u00a0years. Of three patients who underwent salvage transplants, two are alive at 1.5\u00a0years after transplant. Non\u2010survivors were associated with lower median alpha fetoprotein value at presentation compared to survivors (21\u00a0707 vs 343\u00a0214;\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.04). In conclusion, the overall long\u2010term outcome of primary liver transplantation for HB is excellent. Tumor recurrence was the highest contributor to mortality. Even patients with completely treated pulmonary metastases prior to transplant demonstrated a favorable survival.\n                  <\/jats:p>","DOI":"10.1111\/petr.13250","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T04:07:53Z","timestamp":1528690073000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Long\u2010term outcomes of liver transplantation for hepatoblastoma: A single\u2010center 14\u2010year experience"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2988-161X","authenticated-orcid":false,"given":"Gabriel","family":"Ramos\u2010Gonzalez","sequence":"first","affiliation":[{"name":"Department of Surgery Boston Children's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"LaQuaglia","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison F.","family":"O'Neill","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute  Boston MA USA"},{"name":"Department of Hematology\/Oncology Boston Children's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Elisofon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Zurakowski","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital  Boston MA USA"},{"name":"Department of Anesthesia Harvard Medical School  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heung Bae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khashayar","family":"Vakili","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital  Boston MA 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