{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T07:15:28Z","timestamp":1788592528515,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T 32DK007664"],"award-info":[{"award-number":["T 32DK007664"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>ABO\u2010ILT have re\u2010emerged as an alternate option for select patients awaiting transplant. However, treatment protocols for children undergoing deceased donor ABO\u2010ILT are not standardized. We implemented a novel IS protocol for children undergoing deceased donor ABO\u2010ILT based on pretransplant IH titers. Children with high pretransplant IH titers (\u22651:32) underwent an enhanced IS protocol including plasmapheresis, rituximab, IVIG, and mycophenolate, while children with IH titers \u22641:16 received steroids and tacrolimus. We retrospectively assessed our outcomes of ABO\u2010ILT with ABO\u2010compatible recipients of similar age and diagnosis over a 2\u2010year period. Ten children with median age of 8.9\u00a0months underwent ABO\u2010ILT, 4 of 10 patients underwent enhanced IS due to high IH titers. Rates of complications (rejection, infections, biliary, and vascular) at both 1\u00a0year and up to 3\u00a0years post\u2010transplant were comparable between the groups. Patients with ABO\u2010ILT had good graft function with 100% survival at a median follow\u2010up of 3.3\u00a0years. In conclusion, IS tailored to pretransplant IH titers in pediatric deceased donor ABO\u2010ILT is feasible and can achieve outcomes similar to ABO\u2010CLT at 1 and 3\u00a0years post\u2010transplantation.<\/jats:p>","DOI":"10.1111\/petr.13263","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T14:18:52Z","timestamp":1533305932000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["ABO\u2010incompatible deceased donor pediatric liver transplantation: Novel titer\u2010based management protocol and outcomes"],"prefix":"10.1111","volume":"22","author":[{"given":"Krupa R.","family":"Mysore","sequence":"first","affiliation":[{"name":"Section of Pediatric Gastroenterology Texas Children's Hospital Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0116-2613","authenticated-orcid":false,"given":"Ryan W.","family":"Himes","sequence":"additional","affiliation":[{"name":"Section of Pediatric Gastroenterology Texas Children's Hospital Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Rana","sequence":"additional","affiliation":[{"name":"Michael E. 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DeBakey Department of Surgery Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Calvert","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Texas Children's Hospital  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Guffey","sequence":"additional","affiliation":[{"name":"Dan L. Duncan Institute for Clinical and Translational Research Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles G.","family":"Minard","sequence":"additional","affiliation":[{"name":"Dan L. Duncan Institute for Clinical and Translational Research Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eda","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Pathology Transfusion Medicine Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Hensch","sequence":"additional","affiliation":[{"name":"Department of Pathology Transfusion Medicine Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Losos","sequence":"additional","affiliation":[{"name":"Department of Pathology Transfusion Medicine Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vadim","family":"Kostousov","sequence":"additional","affiliation":[{"name":"Department of Pathology Transfusion Medicine Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiu\u2010Ki Rocky","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Pathology Transfusion Medicine Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan S.","family":"Orange","sequence":"additional","affiliation":[{"name":"Section of Pediatric Allergy &amp; Immunology Texas Children's Hospital Baylor College of Medicine  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Goss","sequence":"additional","affiliation":[{"name":"Michael E. 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