{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:42:53Z","timestamp":1753879373009,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T00:00:00Z","timestamp":1532563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>No studies have examined <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection in pediatric patients with <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> receiving <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>. Here, we retrospectively analyzed the incidence of and risk factors for <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection in 24 pediatric patients with <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content> who underwent <jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> between 1997 and 2015. <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection was monitored by measuring expression of pp65 <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> antigen for up to 4\u00a0months post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection, defined as detection of at least one pp65\u2010positive leukocyte, was detected in nine (37.5%) patients who did not develop <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> disease. Nine (47.4%) of nineteen patients who received post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> chemotherapy experienced <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection; however, no <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection was observed in the five patients who did not receive post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> chemotherapy (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.012). There were no significant differences in the incidence of <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection between patients with ACR (60.0%) and those without (21.4%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.092), or between <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> seropositive (55.6%) and seronegative patients (33.3%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.675). All nine patients with <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection did not experience <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> disease due to the use of preemptive antiviral therapy. Close monitoring of <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection is recommended for patients with <jats:styled-content style=\"fixed-case\">HB<\/jats:styled-content>, particularly those receiving post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> chemotherapy. Preemptive antiviral therapy is feasible for prophylaxis of <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> disease.<\/jats:p>","DOI":"10.1111\/petr.13273","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T00:44:58Z","timestamp":1532652298000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cytomegalovirus infection in pediatric patients with hepatoblastoma after liver transplantation"],"prefix":"10.1111","volume":"22","author":[{"given":"Seishiro","family":"Nodomi","sequence":"first","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine Kyoto University  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6844-2011","authenticated-orcid":false,"given":"Katsutsugu","family":"Umeda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Graduate School of Medicine 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