{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:58:48Z","timestamp":1790492328230,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T00:00:00Z","timestamp":1534723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hemophagocytic lymphohistiocytosis (<jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content>), a rare condition characterized by\u00a0immune dysfunction with uncontrolled activation of macrophages and hypersecretion of cytokines, has only been reported in a small number of pediatric patients following solid organ transplant (<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>). The diagnosis of <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> is especially difficult, as several of the diagnostic criteria, including fever, splenomegaly, and cytopenias, are nonspecific and can be seen with other post\u2010transplant complications. Autoimmune hemolytic anemia (<jats:styled-content style=\"fixed-case\">AIHA<\/jats:styled-content>) has also been reported after pediatric <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> and is thought to be related to immunosuppression, specifically tacrolimus. Although <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">AIHA<\/jats:styled-content> have been separately described following <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>, there have been no reports of them occurring together in post\u2013liver transplant (<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>) patients. We report the first case of autoimmune hemolysis as the presenting symptom of <jats:styled-content style=\"fixed-case\">HLH<\/jats:styled-content> in a pediatric post\u2010<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content> patient.<\/jats:p>","DOI":"10.1111\/petr.13281","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T15:18:08Z","timestamp":1534951088000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Autoimmune hemolytic anemia: An unusual presentation of hemophagocytic lymphohistiocytosis in a pediatric post\u2013liver transplant patient"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6452-1217","authenticated-orcid":false,"given":"Lauren","family":"Jarchin","sequence":"first","affiliation":[{"name":"Division of Pediatric Gastroenterology Mount Sinai Medical Center  New York City New 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