{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:32:20Z","timestamp":1753878740374,"version":"3.41.2"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>No studies have reported making use of kidneys from pediatric donors with severe <jats:styled-content style=\"fixed-case\">HFMD<\/jats:styled-content>. Here, we retrospectively analyzed the feasibility and clinical effect of six cases of kidney transplantation from four pediatric donors with severe <jats:styled-content style=\"fixed-case\">HFMD<\/jats:styled-content> in our center between January 2014 and December 2016. The donors\u2019 age ranged from 6\u00a0months to 3\u00a0years and 11\u00a0months. The recipients\u2019 age ranged from 18 to 41\u00a0years. Single kidney transplantation was performed in four recipients, and dual splitting kidney transplantation and en bloc kidney transplantation were performed in two recipients, respectively. During the 1.5\u20104\u00a0years follow\u2010up, all recipients maintained normal kidney allograft function except for one recipient whose allograft was removed due to the allograft artery thrombosis. The survival rates of recipient and allograft were 100% and 83.3%, respectively. None of the six recipients showed any symptoms associated with <jats:styled-content style=\"fixed-case\">HFMD<\/jats:styled-content>. In conclusion, it is feasible to perform kidney transplantation from pediatric donors with severe <jats:styled-content style=\"fixed-case\">HFMD<\/jats:styled-content> to adult recipients with immunity to the pathogens. The clinical effect is satisfactory.<\/jats:p>","DOI":"10.1111\/petr.13386","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T08:16:37Z","timestamp":1552983397000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Satisfactory usage of kidneys from pediatric donors with severe hand foot mouth disease"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7327-7324","authenticated-orcid":false,"given":"Chen","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Urological Organ Transplantation The Second Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bichen","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Hunan Children Hospital Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojie","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Urological Organ Transplantation The Second Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fenghua","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Urological Organ Transplantation The Second Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gongbin","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Urological Organ Transplantation The Second Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Urological Organ Transplantation The Second Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longkai","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Urological Organ Transplantation The Second Xiangya Hospital of Central South University Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1007\/s10096-018-3206-x"},{"doi-asserted-by":"publisher","key":"e_1_2_7_3_1","DOI":"10.1016\/j.ejpn.2018.04.007"},{"doi-asserted-by":"publisher","key":"e_1_2_7_4_1","DOI":"10.1017\/S095026881500028X"},{"unstructured":"World Health Organization.A guide to clinical management and public health response for hand foot and mouth disease (HFMD).2011.http:\/\/www.wpro.who.int\/publications\/docs\/GuidancefortheclinicalmanagementofHFMD.pdf. 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