{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:07:24Z","timestamp":1780506444842,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T00:00:00Z","timestamp":1560988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Varicella and measles infection represents a significant source of morbidity and mortality for pediatric LT recipients. We evaluated the prevalence and correlates of post\u2010transplant immunity in pediatric LT recipients previously immunized against measles (n\u00a0=\u00a072) and varicella (n\u00a0=\u00a067). Sixteen of seventy\u2010two (22%) patients were measles non\u2010immune, and 42\/67 (63%) were varicella non\u2010immune after LT. Median time from LT to titers for measles and varicella was 4.0 and 3.3\u00a0years, respectively. In the measles cohort, non\u2010immune patients received fewer pretransplant vaccine doses (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.026) and were younger at both time of vaccination (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.006) and LT (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.004) compared with immune patients. Upon multivariable analysis, weight\u00a0&gt;\u00a010\u00a0kg at LT (OR 5.91, 95% CI 1.27\u201027.41) and technical variant graft (OR 0.07, 95% CI 0.01\u20100.37) were independently, significantly associated with measles immunity. In the varicella cohort, non\u2010immune patients received fewer pretransplant vaccine doses (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.028), were younger at transplant (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.022), and had less time lapse between their last vaccine and transplant (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.012) compared with immune patients. Upon multivariate analysis, time\u00a0&gt;\u00a01\u00a0year from last vaccine to LT was independently, significantly associated with varicella immunity (OR 3.78, CI 1.30\u201011.01). This study demonstrates that non\u2010immunity to measles and varicella is a prevalent problem after liver transplantation in children and identifies 3 unique risk factors for non\u2010immunity in this high\u2010risk population.<\/jats:p>","DOI":"10.1111\/petr.13490","type":"journal-article","created":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T11:18:16Z","timestamp":1561029496000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Measles, mumps, rubella (vaccine) and varicella vaccines in pediatric liver transplant: An initial analysis of post\u2010transplant immunity"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7629-3178","authenticated-orcid":false,"given":"Jordan K.","family":"Yoeli","sequence":"first","affiliation":[{"name":"School of Medicine University of Colorado Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dor","family":"Yoeli","sequence":"additional","affiliation":[{"name":"School of Medicine University of Colorado Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamir A.","family":"Miloh","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hepatology and Liver Transplant Medicine, Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics Texas Children\u2019s Hospital Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2979-0598","authenticated-orcid":false,"given":"Abbas","family":"Rana","sequence":"additional","affiliation":[{"name":"Division of Abdominal Transplantation and Hepatobiliary Surgery, Michael E DeBakey Department of Surgery Baylor College of Medicine Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Goss","sequence":"additional","affiliation":[{"name":"Division of Abdominal Transplantation and Hepatobiliary Surgery, Michael E DeBakey Department of Surgery Baylor College of Medicine Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flor","family":"Munoz\u2010Rivas","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, Transplant Infectious Diseases, Department of Pediatrics Baylor College of Medicine and Texas Children\u2019s Hospital Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.07.030"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001196"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.12.021"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.02.094"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000078"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit816"},{"key":"e_1_2_9_8_1","unstructured":"Centers for disease control: measles cases and outbreaks.http:\/\/www.cdc.gov\/measles\/cases-outbreaks.html. 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