{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:31:23Z","timestamp":1764174683141,"version":"3.41.2"},"reference-count":6,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fascioliasis is caused by the trematode liver fluke <jats:italic>Fasciola hepatica<\/jats:italic>. Humans are accidental hosts getting infected after ingesting contaminated plants or water. 90 million people in 75 nations are at risk of infection with <jats:italic>F\u00a0hepatica<\/jats:italic>. Immunosuppressed patients are higher risk of acquiring infection and may present with atypical manifestations. Patients can present with hepatic involvement, biliary features or a combination of both. Confirmation of the diagnosis is by demonstration of live parasites or eggs in bile or feces, serology (immunoelectrophoresis, indirect immunofluorescence, indirect hemagglutination), ELISA, typical imaging findings or a combination of any of the above. The drug of choice for treatment is triclabendazole. Fascioliasis should always be considered as a possibility in post\u2010LT patients with findings of hepatobiliary disorder from endemic areas. Unfamiliarity with this infection in non\u2010endemic areas often eludes prompt diagnosis thereby increasing the morbidity. We report the first case of fascioliasis in a pediatric liver transplant recipient leading to graft loss and mortality.<\/jats:p>","DOI":"10.1111\/petr.13521","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T07:20:19Z","timestamp":1561533619000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["An unusual cause of graft loss in pediatric liver transplant recipient\u2014<i>Fasciola hepatica<\/i>"],"prefix":"10.1111","volume":"23","author":[{"given":"Chaya","family":"Kelgeri","sequence":"first","affiliation":[{"name":"Institute of Liver Disease and Transplantation Gleneagles Global Health City Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Valamparampil","sequence":"additional","affiliation":[{"name":"Institute of Liver Disease and Transplantation Gleneagles Global Health City Chennai India"},{"name":"Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre Bharat Institute of Higher Education and Research Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naresh","family":"Shanmugam","sequence":"additional","affiliation":[{"name":"Institute of Liver Disease and Transplantation Gleneagles Global Health City Chennai India"},{"name":"Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre Bharat Institute of Higher Education and Research Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mettu","family":"Srinivas Reddy","sequence":"additional","affiliation":[{"name":"Institute of Liver Disease and Transplantation Gleneagles Global Health City Chennai India"},{"name":"Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre Bharat Institute of Higher Education and Research Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subramanian","family":"Swaminathan","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Gleneagles Global Health City Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Rela","sequence":"additional","affiliation":[{"name":"Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre Bharat Institute of Higher Education and Research Chennai India"},{"name":"Kings College Hospital London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/511859"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1309\/MLFFXA77UBBFH4GP"},{"issue":"4","key":"e_1_2_7_4_1","first-page":"340","article-title":"Epidemiology of human fascioliasis: a review and proposed new classification","volume":"77","author":"Mas\u2010Coma MS","year":"1999","journal-title":"Bull World Health Organ"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2005.01254.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i44.4899"},{"key":"e_1_2_7_7_1","unstructured":"Parasites(2019 January 14).https:\/\/www.cdc.gov\/parasites\/fasciola\/health_professionals\/index.htm. Accessed April 2 2019."}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.13521","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13521","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.13521","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T10:28:29Z","timestamp":1693823309000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.13521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,26]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/petr.13521"],"URL":"https:\/\/doi.org\/10.1111\/petr.13521","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"type":"print","value":"1397-3142"},{"type":"electronic","value":"1399-3046"}],"subject":[],"published":{"date-parts":[[2019,6,26]]},"assertion":[{"value":"2018-12-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13521"}}