{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:58:40Z","timestamp":1787497120011,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A childhood malignancy can rarely progress to ESRD requiring a KT. To date, few reports describe long\u2010term outcomes of pediatric KT recipients with a pretransplant malignancy. Between 1963 and 2015, 884 pediatric (age: 0\u201017\u00a0years old) recipients received 1055 KTs at our institution. KT outcomes were analyzed in children with a pretransplant malignancy. We identified 14 patients who had a pretransplant malignancy prior to KT; the majority were &lt;10\u00a0years old at the time of KT. Ten (71%) patients received their grafts from living donors, the majority of which were related to the recipient. Wilms' tumor was the dominant type of pretransplant malignancy, seen in 50% of patients. The other pretransplant malignancy types were EBV\u2010positive lymphoproliferative disorders, non\u2010EBV\u2010positive lymphoma, leukemia, neuroblastoma, soft\u2010tissue sarcoma, and ovarian cancer. Ten of the 14 patients received chemotherapy as part of their pretransplant malignancy treatment. Graft survival at 1, 3, and 5\u00a0years was 93%, 83%, and 72%, respectively. Patient survival at 1, 5, and 10\u00a0years was 100%, 91%, and 83%, respectively. Six (40%) patients suffered AR following KT; half of them had their first episode of AR within 1\u00a0month of KT. Our single\u2010center experience demonstrates that pediatric KT recipients with a previously treated pretransplant malignancy did not exhibit worse outcomes than other pediatric KT patients.<\/jats:p>","DOI":"10.1111\/petr.13557","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T07:18:16Z","timestamp":1565680696000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Long\u2010term outcomes of pediatric kidney transplant recipients with a pretransplant malignancy"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5076-0938","authenticated-orcid":false,"given":"Oscar K.","family":"Serrano","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Transplantation University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Gannon","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Transplantation University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayokunle S.","family":"Olowofela","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Transplantation University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apoorva","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Transplantation University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Berglund","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Transplantation University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur J.","family":"Matas","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Transplantation University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21219"},{"key":"e_1_2_7_3_1","volume-title":"Cancer facts & figures 2014","author":"American Cancer Society","year":"2014"},{"issue":"3","key":"e_1_2_7_4_1","first-page":"1","article-title":"Renal complications in children with malignancies: single\u2010centre experience","volume":"2","author":"Bark A","year":"2012","journal-title":"J Hematol 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