{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:57:07Z","timestamp":1759010227838,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007403","name":"Dagmar Marshalls Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007403","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Children receiving HCT loose protective immunity to vaccines received pre\u2010HCT. Therefore, revaccination post\u2010HCT is of major importance. In Denmark, a vaccination schedule with fewer doses post\u2010HCT has been used, including two doses for diphtheria, tetanus, polio, measles, mumps, and rubella, and one dose only for <jats:italic>Haemophilus influenzae<\/jats:italic> type B. The background for this was the presumption that post\u2010HCT immunization constituted booster vaccination of donor immunity. Our objective was to evaluate the proportion of children protected after the scheduled vaccination programme. A nationwide retrospective cohort study of all children who have received an HCT in Denmark during 1994\u20102012. Antibody levels were analysed in blood samples drawn before and after vaccination, and the probability of achieving protection after the scheduled immunization programme was estimated. A total of 198 children were included. The protection post\u2010immunization was as follows: diphtheria 75.3%, tetanus 89.1%, polio 97.7%, and <jats:italic>Haemophilus influenzae<\/jats:italic> type B 94.8%. For diphtheria and tetanus, the probability of achieving protection increased to 93.8% and 97.3%, respectively, after a third dose. For measles, mumps, and rubella, the probability of achieving protection was 89.4%, 80.9%, and 94.2%, respectively. In conclusion, our findings support a more extensive vaccination schedule including three doses for diphtheria and tetanus which are in line with current international guidelines.<\/jats:p>","DOI":"10.1111\/petr.13599","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T08:31:00Z","timestamp":1571214660000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Antibody response to vaccination after haematopoietic cell transplantation in children using a reduced dose schedule\u2014A retrospective cohort study"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7855-4036","authenticated-orcid":false,"given":"Lotte","family":"Jensen","sequence":"first","affiliation":[{"name":"The Department of Paediatrics and Adolescent Medicine Juliane Marie Centre Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"},{"name":"Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Poulsen","sequence":"additional","affiliation":[{"name":"The Department of Paediatrics and Adolescent Medicine Juliane Marie Centre Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrikka","family":"Nygaard","sequence":"additional","affiliation":[{"name":"The Department of Paediatrics and Adolescent Medicine Juliane Marie Centre Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"},{"name":"Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Scheike","sequence":"additional","affiliation":[{"name":"Section of Biostatistics Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margit Schilling","family":"Riis","sequence":"additional","affiliation":[{"name":"Section of Biostatistics Department of Public Health University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Freddy Karup","family":"Pedersen","sequence":"additional","affiliation":[{"name":"The Department of Paediatrics and Adolescent Medicine Juliane Marie Centre Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carsten","family":"Heilmann","sequence":"additional","affiliation":[{"name":"The Department of Paediatrics and Adolescent Medicine Juliane Marie Centre Rigshospitalet, Copenhagen University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"D'SouzaA ZhuX.Current Uses and Outcomes of Hematopoietic Cell Transplantation (HCT): CIBMTR Summary Slides;2016. [Internet]. CIBMTR (Center for International Blood and Marrow Transplant Research).http:\/\/www.cibmtr.org. 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[Internet].https:\/\/www.ssi.dk\/vaccinationer\/boernevaccination\/vaccinationsdaekning-og-aarsraporter\/historisk-oversigt. Accessed June 27 2019."},{"key":"e_1_2_8_17_1","unstructured":"BorrowR BalmerP RoperMH.World Health Organization Department of Immunization V and B. Immunological basis for immunization: Molule 3\u202f: Tetanus (update 2006). Geneva: World Health Organization;2007."},{"key":"e_1_2_8_18_1","unstructured":"WHOWHO | <strong>ISBN 978 92 4 159786 9<\/strong>. [Internet]. WHO.http:\/\/www.who.int\/immunization\/documents\/ISBN9789241597869\/en\/. 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