{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:55:59Z","timestamp":1787316959618,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006823","name":"Boston Children's Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006823","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Hepatic artery thrombosis (HAT) following pediatric liver transplantation increases morbidity and risk of graft failure. We performed a retrospective chart review of all patients who underwent deceased\u2010donor liver transplantation from August 2002 to July 2016. Multi\u2010organ transplant recipients were excluded. We examined the incidence of HAT at our institution and sought to identify associated donor or recipient risk factors. A total of 127 deceased\u2010donor liver transplant patients with a median age of 1.7\u00a0years (IQR 0.67\u20106.7) were identified. Of those, 14 developed HAT, all weighing under 25\u00a0kg. Among 100 patients under 25\u00a0kg, whole\u2010liver graft recipients had an odds ratio of 3.98 (95% confidence interval [CI]: 1.03, 15.34;\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.045) for developing HAT compared with split\u2010liver graft recipients. Within the whole\u2010liver recipient group under 25\u00a0kg, 11 patients developed HAT with a median donor\u2010to\u2010recipient ratio (DRWR) of 0.9 (IQR: 0.7\u20101.2) compared with a median DRWR of 1.4 (IQR: 1.1\u20101.9) for those who did not develop HAT. Multivariate analysis showed DRWR to be an independent risk factor for HAT in patients weighing under 25\u00a0kg who received whole organ grafts, with an odds ratio of 3.89 (95% CI: 1.43, 10.54;\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.008) for each 0.5 unit decrease in DRWR. Our results suggest that in recipients under 25\u00a0kg 1) split\u2010liver grafts may have a lower rate of HAT and 2) selecting whole organ donors with a higher DRWR may decrease the incidence of HAT.\n                  <\/jats:p>","DOI":"10.1111\/petr.13623","type":"journal-article","created":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T01:39:58Z","timestamp":1576114798000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Donor\u2010to\u2010recipient weight ratio is a risk factor for hepatic artery thrombosis after whole\u2010liver transplantation in children under 25\u00a0kg"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5201-7707","authenticated-orcid":false,"given":"Stephanie S.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Surgery Boston Children's Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Ramos\u2010Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Staffa","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital Boston Massachusetts"},{"name":"Department of Anesthesiology, Critical Care and Pain Medicine Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Labib","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heung Bae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khashayar","family":"Vakili","sequence":"additional","affiliation":[{"name":"Department of Surgery Boston Children's Hospital Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23393"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.1998.tb01126.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200103270-00014"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2003.50057"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2008.12.032"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.06.014"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.139.10.1069"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198906000-00011"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001135"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02541.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90364-J"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9261.154651"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12459"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jped.2013.08.010"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198512000-00019"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199101000-00013"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22063"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2012.06.045"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2008.00924.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12908"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.03.003"}],"container-title":["Pediatric 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