{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:42:55Z","timestamp":1753879375409,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T00:00:00Z","timestamp":1595894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a case of pediatric ALF, secondary to hepatic HL, who underwent a successful ABOi living donor liver transplant. We believe this is the first such case reported in academic literature. HL with liver involvement is extremely rare and is not considered an indication for transplantation. The 12\u2010year\u2010old, male patient presented with a viral illness prodrome, and parvovirus was detected in pre\u2010transplant laboratory cultures. He received an ABOi living donor liver graft followed by a course of plasma exchange and rituximab after which standard immunosuppression was used. The HL was diagnosed on hepatic biopsy post\u2010transplant. Subsequently, the patient commenced six cycles of R\u2010CHOP chemotherapy. During chemotherapy, we stopped tacrolimus and mycophenolate mofetil. Immunosuppression was maintained with corticosteroids in\u2010between cycles. The patient is alive and reports good quality of life 1\u2010year post\u2010transplant. The HL is in remission. During the post\u2010operative period, the patient experienced four episodes of neutropenia, a bile leak, and gram\u2010negative sepsis. One episode of acute rejection has been treated. Although we did not initially transplant the patient for ALF secondary to HL, its subsequent diagnosis and the patient's response to management raises many issues that warrant consideration. While the findings from a single case cannot be generalized, this could be a \u201cproof of concept\u201d for liver transplantation in hepatic HL. We hope it will facilitate discussions and potentially expand therapeutic options available to this very small group patients.<\/jats:p>","DOI":"10.1111\/petr.13796","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:23:42Z","timestamp":1595982222000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Successful ABO\u2010incompatible living donor liver transplant for acute liver failure secondary to Hodgkin's Lymphoma in a child"],"prefix":"10.1111","volume":"24","author":[{"given":"Lliam","family":"Brannigan","sequence":"first","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2581-5754","authenticated-orcid":false,"given":"Harriet R.","family":"Etheredge","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"},{"name":"Department of Internal Medicine School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Beretta","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despina","family":"Demopoulos","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate G.","family":"Bennett","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Beringer","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marelize","family":"Reynders","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean F.","family":"Botha","sequence":"additional","affiliation":[{"name":"Wits Donald Gordon Medical Centre School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"},{"name":"Department of Surgery School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02093804"},{"key":"e_1_2_9_3_1","unstructured":"Wits Donald Gordon Medical Centre.Registry of Transplant Recipients Annual Report: Adult Liver Transplantation December 2018.http:\/\/www.dgmc.co.za\/ContentClinical\/documents\/AdultLiverTransplantReport2018.pdf. Accessed February 13 2020."},{"key":"e_1_2_9_4_1","unstructured":"Wits Donald Gordon Medical Centre.Registry of Transplant Recipients Annual Report: Paediatric Liver Transplantation December 2018.http:\/\/www.dgmc.co.za\/ContentClinical\/documents\/Paed\u2010Liver\u2010Transplant\u2010Report\u2010December2018\u201012\u2010v1.pdf. Accessed February 13 2020."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/484903"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4081\/hr.2010.e5"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2013.19.3.320"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-209328"},{"issue":"1","key":"e_1_2_9_9_1","article-title":"The CARE Guidelines: Consensus\u2010based clinical case reporting guideline development","volume":"7","author":"Gagnier JJ","year":"2013","journal-title":"BMJ Case Rep"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.07.002"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000173999.09381.95"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2010.01380.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002526"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.7196\/sajbl.534"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fpetr.13796","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13796","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.13796","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13796","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T18:24:33Z","timestamp":1693765473000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.13796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,28]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/petr.13796"],"URL":"https:\/\/doi.org\/10.1111\/petr.13796","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"type":"print","value":"1397-3142"},{"type":"electronic","value":"1399-3046"}],"subject":[],"published":{"date-parts":[[2020,7,28]]},"assertion":[{"value":"2020-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13796"}}