{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:27:34Z","timestamp":1761845254585,"version":"3.41.2"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T00:00:00Z","timestamp":1598400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008750","name":"Shanghai Hospital Development Center","doi-asserted-by":"publisher","award":["16CR3109B"],"award-info":[{"award-number":["16CR3109B"]}],"id":[{"id":"10.13039\/501100008750","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81900594"],"award-info":[{"award-number":["81900594"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To investigate the role of two\u2010dimensional shear wave elastography (2D\u2010SWE) in the preoperative evaluation of pediatric patients with biliary atresia awaiting liver transplantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among a total of 152 pediatric patients enrolled in this single\u2010institution prospective study between March 2018 and August 2019, 143 patients (age range, 4\u201097\u00a0months; median age, 7\u00a0months; 84 males, 59 females) who underwent successful routine ultrasound examination, SWE examination, and blood test before liver transplantation were included in the final analysis. The values of liver stiffness measured by SWE were compared with ultrasound and blood test parameters by Spearman's correlation analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall median liver stiffness with 2D\u2010SWE was 29.0\u00a0\u00b1\u00a010.9\u00a0kPa, with a range of 9.0\u201053.3\u00a0kPa. The success rate of 2D\u2010SWE measurements was 98.0% (149\/152). Liver stiffness measurement (LSMs) had no significant correlation with gender, age, weight, and height of the pediatric recipients. LSMs were correlated with ultrasound parameters including portal vein (PV) maximum velocity, PV direction, hepatic artery resistance index (HARI), spleen diameter, ascites, and blood test parameters (albumin level, platelet count level, and international normalized ratio). In the pediatric recipients with hepatofugal PV flow, high HARI (HARI\u00a0\u2267\u00a00.90), and ascites, or without Kasai operation, LSMs were significantly higher (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SWE is feasible and valuable for assessing liver damage in children with biliary atresia awaiting liver transplantation and might be used as selection criteria for children in need of priority access to liver transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.13815","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T17:29:11Z","timestamp":1599067751000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Shear wave elastography for evaluation of the urgency of liver transplantation in pediatric patients with biliary atresia"],"prefix":"10.1111","volume":"24","author":[{"given":"Li\u2010hong","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Liver Surgery Renji Hospital School of Medicine Shanghai Jiaotong University Shanghai China"},{"name":"Department of Ultrasound Renji Hospital School of Medicine Shanghai Jiaotong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang\u2010xiang","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Liver Surgery Renji Hospital School of Medicine Shanghai Jiaotong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Renji Hospital School of Medicine Shanghai Jiaotong University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Liver 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