{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T08:56:58Z","timestamp":1784105818885,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,10,18]],"date-time":"2020-10-18T00:00:00Z","timestamp":1602979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Minimal data exist on clinical decision\u2010making in VAD implantation in pediatrics. This study aims to identify areas of consensus\/variability among pediatric VAD physicians in determining eligibility and factors that guide decision\u2010making.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An 88\u2010item survey with clinical vignettes was sent to 132 pediatric HT cardiologists and surgeons at 37 centers. Summary statistics are presented for the variables assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total respondents were 65 (72% cardiologists, 28% surgeons) whose centers implanted 1\u20105 (34%), 6\u201010 (40%), or &gt;10 (26%) VADs in the past year. Consensus varied by patients\u2019 age, diagnosis, and Pedimacs profile. Highest agreement to offer VAD (97%) was a mechanically ventilated teenager with dilated cardiomyopathy. Patients stable on inotropes were less likely offered VAD (11%\u201025%). SV infant with Pedimacs profile 2 had the most varied responses: 37% offered VAD; estimated survival ranged from 15% to 90%. Variables considered for VAD eligibility included mild developmental delays (100% offered VAD), moderate\u2010severe behavioral concerns (46%), cancer in remission &gt;2\u00a0years (100%), active malignancy with good prognosis (68%) or uncertain prognosis (36%), and BMI &gt;35 (74%) or &lt;15 (69%). Most respondents (91%) would consider destination therapy VADs in pediatrics, though not currently feasible at 1\/3 of centers. Factors with greatest influence on decision\u2010making included HT candidacy, families\u2019 goals of care, and risks of complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Significant variation exists among pediatric VAD physicians when determining VAD eligibility and estimating survival, which can lead to differences in access to emerging technologies across institutions. Further work is needed to understand and mitigate these differences.<\/jats:p><\/jats:sec>","DOI":"10.1111\/petr.13840","type":"journal-article","created":{"date-parts":[[2020,10,18]],"date-time":"2020-10-18T10:19:18Z","timestamp":1603016358000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Variability in clinical decision\u2010making for ventricular assist device implantation in pediatrics"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2223-0045","authenticated-orcid":false,"given":"Anna","family":"Joong","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Northwestern Feinberg School of Medicine Ann &amp; Robert H. 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