{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T14:04:01Z","timestamp":1767276241193,"version":"3.41.2"},"reference-count":71,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Substance abuse is infrequently addressed during pre\u2010 and post\u2010transplant care. However, the significant increase in the use of nicotine\u2010 and marijuana\u2010containing products in the general and transplant adolescent population is concerning. In addition, alcohol use\/abuse remains prevalent in the US population as it is highly accessible. Pediatric transplant providers should be prepared to screen for the use of any of these substances (eg, alcohol, nicotine, marijuana, cocaine, opiates, amphetamines) and to counsel them about the dangers of substance use and abuse including the unique dangers of the substances as a transplant recipient. Formal screening tools (in children as young as 9\u00a0years) should always be used as casual assessment of substance abuse has a high failure rate. This review summarizes the substances most commonly used in adolescent transplant recipients and the approach that transplant providers should take in order to prevent, decrease, or halt use in this patient population.<\/jats:p>","DOI":"10.1111\/petr.13877","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T20:21:30Z","timestamp":1603743690000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Substance use and abuse in pediatric transplant recipients: What the transplant provider needs to know"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0519-7271","authenticated-orcid":false,"given":"Nicole","family":"Hayde","sequence":"first","affiliation":[{"name":"Children\u2019s Hospital at Montefiore Bronx NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2014(Sup01)06"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182719203"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209963"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1910739"},{"key":"e_1_2_10_6_1","first-page":"2017","article-title":"Trends in reported marijuana vaping among US adolescents, 2017\u20132019","volume":"323","author":"Miech RA","year":"2019","journal-title":"JAMA"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2020.01.007"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2019.107431"},{"volume-title":"Monitoring the Future National Survey: Trends in 30\u2010Day Prevalence of Use of Various Drugs in Grades 8, 10, and 12. Table 3","year":"2019","author":"Miech RA","key":"e_1_2_10_9_1"},{"key":"e_1_2_10_10_1","unstructured":"Methodology: Population prevalence estimates (%) are weighted by the person\u2010level analysis weight and derived from the Center for Behavioral Health Statistics and Quality National Survey on Drug Use and Health 2018 (NSDUH\u20102018\u2010DS0001) Public\u2010Use File Dataset. Lifetime alcohol use is defined as ever even once having had a drink of any type of alcoholic beverage (a can or bottle of beer a glass of wine or a wine cooler a shot of distilled spirits or a mixed drink with distilled spirits in it) not counting a sip or two from a drink.https:\/\/www.datafiles.samhsa.gov\/study\u2010dataset\/national\u2010survey\u2010drug\u2010use\u2010and\u2010health\u20102018\u2010nsduh\u20102018\u2010ds0001\u2010nid18758"},{"key":"e_1_2_10_11_1","unstructured":"Substance Abuse and Mental Health Services Administration (SAMHSA).2018 National Survey on Drug Use and Health. Table 7.16A\u2014Alcohol Use in Lifetime Past Year and Past Month among Persons Aged 12 to 20 by Gender: Numbers in Thousands 2002\u20102018.https:\/\/www.samhsa.gov\/data\/sites\/default\/files\/cbhsq\u2010reports\/NSDUHDetailedTabs2018R2\/NSDUHDetTabsSect7pe2018.htm#tab7\u201016a"},{"volume-title":"Alcohol and Public Health: Alcohol\u2010Related Disease Impact (ARDI)","year":"2016","author":"Centers for Disease Control and Prevention (CDC)","key":"e_1_2_10_12_1"},{"volume-title":"The DAWN Report: Highlights of the 2014 Drug Abuse Warning Network (DAWN) Findings on Drug\u2010Related Emergency Department Visits","year":"2014","author":"SAMHSA, Center for Behavioral Health Statistics and Quality","key":"e_1_2_10_13_1"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2016.01.029"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-4026"},{"key":"e_1_2_10_16_1","unstructured":"Substance Abuse and Mental Health Services Administration.The dawn report: alcohol and drug combinations are more likely to have a serious outcome than alcohol alone in emergency department visits involving underage drinking;2014."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15590"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-0722"},{"issue":"2","key":"e_1_2_10_19_1","first-page":"135","article-title":"The risks associated with alcohol use and alcoholism","volume":"34","author":"Rehm J","year":"2011","journal-title":"Alcohol Res Health"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1715733"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31829f7579"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl689"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2019.02.011"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-1211"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2014.774"},{"volume-title":"Preventing Tobacoo Use Among Youth and Adults: A Report of the Surgeon General","year":"2012","author":"U.S. Department of Health & Human Services","key":"e_1_2_10_26_1"},{"volume-title":"Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products","year":"2015","author":"Institute of Medicine (IOM)","key":"e_1_2_10_27_1"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.11.013"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1000079"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntz127"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826084.2016.1214152"},{"issue":"4","key":"e_1_2_10_32_1","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1681\/ASN.V114753","article-title":"Cigarette smoking in renal transplant recipients","volume":"11","author":"Kasiske BL","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2002.34150"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22140"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0178570"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2006.06.008"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(97)00156-5"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199810150-00033"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03701.x"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2017.09.043"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60160-3"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2017.09.021"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182751f1f"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201210-1865OC"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2121"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13456"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010716-104615"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.3109\/10673220903463259"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.00721.x"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e3282f56139"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02468.x"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12828"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198102193040812"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428190109097776"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1155\/2000\/248915"},{"key":"e_1_2_10_56_1","first-page":"4028492","article-title":"High on cannabis and calcineurin inhibitors: a word of warning in an era of legalized marijuana","volume":"2016","author":"Hauser N","year":"2016","journal-title":"Case Rep Transplant"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2010.05.006"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.3A0115-030RR"},{"key":"e_1_2_10_59_1","unstructured":"NewmanJ.History of the Electronic Cigarette. The IHL Hockey website;2013."},{"key":"e_1_2_10_60_1","unstructured":"Centers for Disease Control and Prevention.National Youth Tobacco Survey 2017. Analysis by the American Lung Association Epidemiology and Statistics Unit using SPSS software."},{"issue":"08","key":"e_1_2_10_61_1","article-title":"Youth risk behavior surveillance\u2014United States, 2017","volume":"67","author":"Centers for Disease Control and Prevention","year":"2018","journal-title":"Morb Mortal Wkly Rep"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.01130"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.6b00489"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6843e1"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6903e2"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1916433"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14714"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.04.049"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.55.3.3"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1991.03460090100040"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta13060"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0098"}],"container-title":["Pediatric Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13877","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/petr.13877","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/petr.13877","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T18:45:03Z","timestamp":1693766703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/petr.13877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,26]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/petr.13877"],"URL":"https:\/\/doi.org\/10.1111\/petr.13877","archive":["Portico"],"relation":{},"ISSN":["1397-3142","1399-3046"],"issn-type":[{"type":"print","value":"1397-3142"},{"type":"electronic","value":"1399-3046"}],"subject":[],"published":{"date-parts":[[2020,10,26]]},"assertion":[{"value":"2020-06-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13877"}}