{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:33:01Z","timestamp":1753878781354,"version":"3.41.2"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T00:00:00Z","timestamp":1604275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Graft loss characterized by sudden deterioration after initial favorable recovery of the allograft function within the first week after liver transplantation was reported as \u201cseventh\u2010day syndrome.\u201d The outcome of seventh\u2010day syndrome is extremely poor, and its etiology and management are not still established. We herein reported a seventh\u2010day syndrome case who was successfully managed by immediate desensitization after liver retransplantation and reviewed by English literature. A 19\u2010year\u2010old woman who had underwent the first liver transplantation when she was 2\u2010year\u2010old. She developed graft failure due to chronic rejection and was on the waiting list for retransplantation. An evaluation of panel\u2010reactive antibody showed high positivity, but there were no preformed donor\u2010specific antibodies. Plasma exchange was performed one\u2010time just before retransplantation and the mean fluorescence intensity significantly decreased. The second liver was successfully transplanted, and post\u2010operative course was uneventful. However, on post\u2010operative day 5, her body temperature elevated and thereafter, her liver enzymes dramatically elevated. We immediately started a desensitization consisted of plasma exchange, intravenous immunoglobulin, and anti\u2010CD20 antibody. The peak level of AST and ALT was 5799\u00a0IU\/L and 3960\u00a0IU\/L, respectively. The pathological findings of liver biopsy revealed some central venous endotheliitis and massive centrilobular hemorrhagic hepatocellular necrosis. These findings were not typical for antibody\u2010mediated rejection, but the desensitization was effective and liver graft was successfully rescued. The only way to prevent early graft loss due to seventh\u2010day syndrome is thought to be an immediate decision to start intensive desensitization.<\/jats:p>","DOI":"10.1111\/petr.13907","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T13:25:09Z","timestamp":1604323509000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Successful management to prevent early graft loss due to Seventh\u2010day Syndrome after liver retransplantation: A case report and literature review"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4937-3890","authenticated-orcid":false,"given":"Toshiharu","family":"Matsuura","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Kohashi","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8709-7313","authenticated-orcid":false,"given":"Koichiro","family":"Yoshimaru","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoharu","family":"Yoshizumi","sequence":"additional","affiliation":[{"name":"Department of Surgery and Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinao","family":"Oda","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Surgery and Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoaki","family":"Taguchi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Graduate School of Medical Sciences Kyushu University Fukuoka Japan"},{"name":"Fukuoka College of Health Sciences Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,11,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0676.2001.210102.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13909"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.42.4.360"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199605150-00015"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2006.08.169"},{"key":"e_1_2_8_7_1","first-page":"22","article-title":"Potential etiopathogenesis of seventh day syndrome following living donor liver transplantation: ischemia of the graft?","volume":"9","author":"Lan X","year":"2010","journal-title":"Hepatobiliary Pancreat Dis 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