{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:24:06Z","timestamp":1787729046229,"version":"build-2784847793"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007786","name":"National Center for Child Health and Development","doi-asserted-by":"publisher","award":["30\u20102"],"award-info":[{"award-number":["30\u20102"]}],"id":[{"id":"10.13039\/100007786","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Transplantation"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Recent guidelines suggest that LAVs may be given to LT recipients meeting certain criteria. However, information is still limited. We sought to evaluate the safety of LAVs, including measles, mumps, rubella, and varicella to LT recipients following our clinically based immunization protocol for LT recipients. We conducted a case\u2010series analysis on safety of LAVs for measles, rubella, varicella, and mumps given to LT recipients at our institution from July 2010 to July 2019. Patients who underwent LT at age &lt;20\u00a0years who visited our immunization clinic were included. LT recipients were vaccinated if 2\u00a0years had lapsed from LT, had no signs of rejection within 6\u00a0months, and were on minimal immunosuppressants. Patient demographics, underlying diseases, type and number of vaccines administered, date of vaccination, and adverse events occurring within 4\u00a0weeks after vaccination were extracted from their medical records. During the study period, LAVs were administered 422 times to 209 patients who met criteria and included 225 doses of MR combination vaccine, 224 doses of varicella vaccine, and 215 doses of mumps vaccine. Underlying diseases included cholestatic liver diseases (n\u00a0=\u00a0125), followed by metabolic diseases (n\u00a0=\u00a033) and acute liver failure (n\u00a0=\u00a019). Nine non\u2010critical adverse events (2.1%) possibly associated with LAVs were reported, but there were no serious adverse events, including hospitalizations or deaths. In conclusion, LAVs administered to LT recipients were safe without any serious adverse events following our relatively simple institutional protocol.<\/jats:p>","DOI":"10.1111\/petr.13937","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T13:59:07Z","timestamp":1607781547000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Safety of LAVs administered after pediatric LT"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6598-5187","authenticated-orcid":false,"given":"Takanori","family":"Funaki","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases Department of Medical Subspecialties National Center for Child Health and Development Setagaya\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7164-0262","authenticated-orcid":false,"given":"Kensuke","family":"Shoji","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medical Subspecialties National Center for Child Health and Development Setagaya\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4684-0446","authenticated-orcid":false,"given":"Akinari","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Center for Organ Transplantation National Center for Child Health and Development Setagaya\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3031-7319","authenticated-orcid":false,"given":"Seisuke","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Center for Organ Transplantation National Center for Child Health and Development Setagaya\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1651-0430","authenticated-orcid":false,"given":"Mureo","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Center for Organ Transplantation National Center for Child Health and Development Setagaya\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3886-9089","authenticated-orcid":false,"given":"Isao","family":"Miyairi","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medical Subspecialties National Center for Child Health and Development Setagaya\u2010ku Japan"},{"name":"Department of Microbiology, Immunology, and Biochemistry University of Tennessee Health Science Center Memphis TN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra064928"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit816"},{"key":"e_1_2_9_4_1","volume-title":"Immunization guideline for pediatric organ transplant recipients and immunocompromised patients","author":"JSPID guideline development committee","year":"2014"},{"key":"e_1_2_9_5_1","unstructured":"Australian Immunisation Handbook.Vaccination for people who are immunocompromised.https:\/\/immunisationhandbook.health.gov.au\/vaccination\u2010for\u2010special\u2010risk\u2010groups\/vaccination\u2010for\u2010people\u2010who\u2010are\u2010immunocompromised. 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A prospective interventional cohort study demonstrating the safety and immunogenicity of measles vaccine in children after liver transplantation","volume":"21","author":"Pillet L","year":"2017","journal-title":"Pediatr Transplant"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15101"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04273.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2005.00403.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.12930"},{"key":"e_1_2_9_20_1","unstructured":"US Food and Drug Administration.Guidance for industry: toxicity grading scale for healthy adult and adolescent volunteers enrolled in preventive vaccine clinical trials. 2007.https:\/\/www.fda.gov\/media\/73679\/download. 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